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Application of in vivo methodologies to investigation of biological structure, function and xenobiotic response in see-through medaka (Oryzias latipes)
https://doi.org/10.18999/fisbjm.11.43
https://doi.org/10.18999/fisbjm.11.43550dc8ab-84c8-4be1-bedf-0129fa4a9006
名前 / ファイル | ライセンス | アクション |
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KJ00005673809.pdf (4.2 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2010-06-22 | |||||
タイトル | ||||||
タイトル | Application of in vivo methodologies to investigation of biological structure, function and xenobiotic response in see-through medaka (Oryzias latipes) | |||||
言語 | en | |||||
著者 |
Hardman, Ron C.
× Hardman, Ron C.× Kullman, Seth. W.× Hinton, David E. |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | Laboratory of Freshwater Fish Stocks Bioscience and Biotechnology Center Nagoya University | |||||
権利 | ||||||
言語 | ja | |||||
権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | medaka | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | liver | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | toxicity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatobiliary | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | in vivo imaging | |||||
抄録 | ||||||
内容記述 | We describe here the development and application of non invasive in vivo methodologies to the investigation of biological structure, function and xenobiotic response in see-through medaka (STII; Oryzias latipes). In vivo studies in STII medaka provided novel insights into hepatobiliary architecture, development and toxic response, in both 2 and 3 dimensions. As the presented findings suggest, STII medaka provide a unique means for high resolution in vivo study, and the future opportunity to integrate mechanisms of toxicity (e.g. genomic, proteomic information) with phenotypic changes at the system level (the overarching goal of our laboratory). While our focus has been the hepatobiliary system, other organ systems are equally amenable to in vivo study, and we consider the potential for discovery, within the context of in vivo investigation in STII medaka, as significant. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Laboratory of Freshwater Fish Stocks Bioscience and Biotechnology Center Nagoya University | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/fisbjm.11.43 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://ci.nii.ac.jp/naid/110007349047/ | |||||
書誌情報 |
en : The Fish Biology Journal Medaka 巻 11, p. 43-65, 発行日 2007 |
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フォーマット | ||||||
application/pdf | ||||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/13836 | |||||
識別子タイプ | HDL |