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  1. H180 生物機能開発利用研究センター
  2. H180b 紀要
  3. The fish biology journal Medaka
  4. 11

Application of in vivo methodologies to investigation of biological structure, function and xenobiotic response in see-through medaka (Oryzias latipes)

https://doi.org/10.18999/fisbjm.11.43
https://doi.org/10.18999/fisbjm.11.43
550dc8ab-84c8-4be1-bedf-0129fa4a9006
名前 / ファイル ライセンス アクション
KJ00005673809.pdf KJ00005673809.pdf (4.2 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2010-06-22
タイトル
タイトル Application of in vivo methodologies to investigation of biological structure, function and xenobiotic response in see-through medaka (Oryzias latipes)
言語 en
著者 Hardman, Ron C.

× Hardman, Ron C.

WEKO 37906

en Hardman, Ron C.

Search repository
Kullman, Seth. W.

× Kullman, Seth. W.

WEKO 37907

en Kullman, Seth. W.

Search repository
Hinton, David E.

× Hinton, David E.

WEKO 37908

en Hinton, David E.

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 Laboratory of Freshwater Fish Stocks Bioscience and Biotechnology Center Nagoya University
権利
言語 ja
権利情報 本文データは学協会の許諾に基づきCiNiiから複製したものである
キーワード
主題Scheme Other
主題 medaka
キーワード
主題Scheme Other
主題 liver
キーワード
主題Scheme Other
主題 toxicity
キーワード
主題Scheme Other
主題 hepatobiliary
キーワード
主題Scheme Other
主題 in vivo imaging
抄録
内容記述 We describe here the development and application of non invasive in vivo methodologies to the investigation of biological structure, function and xenobiotic response in see-through medaka (STII; Oryzias latipes). In vivo studies in STII medaka provided novel insights into hepatobiliary architecture, development and toxic response, in both 2 and 3 dimensions. As the presented findings suggest, STII medaka provide a unique means for high resolution in vivo study, and the future opportunity to integrate mechanisms of toxicity (e.g. genomic, proteomic information) with phenotypic changes at the system level (the overarching goal of our laboratory). While our focus has been the hepatobiliary system, other organ systems are equally amenable to in vivo study, and we consider the potential for discovery, within the context of in vivo investigation in STII medaka, as significant.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Laboratory of Freshwater Fish Stocks Bioscience and Biotechnology Center Nagoya University
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/fisbjm.11.43
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://ci.nii.ac.jp/naid/110007349047/
書誌情報 en : The Fish Biology Journal Medaka

巻 11, p. 43-65, 発行日 2007
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/13836
識別子タイプ HDL
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