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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 72(3-4)

Role of Insulin Resistance in Non-Obese Adolescents

https://doi.org/10.18999/nagjms.72.3-4.161
https://doi.org/10.18999/nagjms.72.3-4.161
2a46cde4-ea50-4af1-8c92-714a74c7fa3f
名前 / ファイル ライセンス アクション
p161-166_Baba.pdf p161-166_Baba.pdf (61.3 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2010-09-21
タイトル
タイトル Role of Insulin Resistance in Non-Obese Adolescents
著者 Baba, Reizo

× Baba, Reizo

WEKO 38873

Baba, Reizo

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Koketsu, Masaaki

× Koketsu, Masaaki

WEKO 38874

Koketsu, Masaaki

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Nagashima, Masami

× Nagashima, Masami

WEKO 38875

Nagashima, Masami

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Tamakoshi, Akiko

× Tamakoshi, Akiko

WEKO 38876

Tamakoshi, Akiko

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Inasaka, Hiroshi

× Inasaka, Hiroshi

WEKO 38877

Inasaka, Hiroshi

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キーワード
主題Scheme Other
主題 Insulin resistance
キーワード
主題Scheme Other
主題 Adolescents
キーワード
主題Scheme Other
主題 Obesity
キーワード
主題Scheme Other
主題 Metabolic syndrome
キーワード
主題Scheme Other
主題 Hypertension
抄録
内容記述 Insulin resistance in the obese is closely related with cardiovascular diseases and their risk factors not only in adults but also in children and adolescents. We aimed to elucidate whether insulin resistance in non-obese adolescents is related with these conditions. A total of 74 non-obese high-school students (38 boys and 36 girls) were recruited. Anthropometry, blood pressure, fasting serum chemistry and insulin activity were measured. Subjects with a homeostasis model assessment-insulin resistance (HOMA-IR) level greater than the 75th percentile (> 2.25 for boys and > 2.89 for girls) were defined as insulin resistant. Non-obese boys with impaired insulin sensitivity had higher systolic blood pressure, lower HDL-cholesterol concentration, and fewer hours of vigorous exercise during weekdays, while non-obese girls with impaired insulin sensitivity had higher systolic blood pressure than their peers with normal insulin sensitivity. By multiple stepwise regression analysis, systolic blood pressure (p<0.001) and the hours of vigorous exercise during weekdays (p<0.03) were independently associated with HOMA-IR in boys, while systolic blood pressure (p<0.0001) and serum concentrations of HDL-cholesterol (p<0.01) were found in girls. In nonobese adolescents, insulin sensitivity is related with cardiovascular risk factors.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.72.3-4.161
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 72, 号 3-4, p. 161-166, 発行日 2010-08
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/14178
識別子タイプ HDL
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