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Role of Insulin Resistance in Non-Obese Adolescents
https://doi.org/10.18999/nagjms.72.3-4.161
https://doi.org/10.18999/nagjms.72.3-4.1612a46cde4-ea50-4af1-8c92-714a74c7fa3f
名前 / ファイル | ライセンス | アクション |
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p161-166_Baba.pdf (61.3 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2010-09-21 | |||||
タイトル | ||||||
タイトル | Role of Insulin Resistance in Non-Obese Adolescents | |||||
言語 | en | |||||
著者 |
Baba, Reizo
× Baba, Reizo× Koketsu, Masaaki× Nagashima, Masami× Tamakoshi, Akiko× Inasaka, Hiroshi |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Insulin resistance | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Adolescents | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Obesity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Metabolic syndrome | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hypertension | |||||
抄録 | ||||||
内容記述 | Insulin resistance in the obese is closely related with cardiovascular diseases and their risk factors not only in adults but also in children and adolescents. We aimed to elucidate whether insulin resistance in non-obese adolescents is related with these conditions. A total of 74 non-obese high-school students (38 boys and 36 girls) were recruited. Anthropometry, blood pressure, fasting serum chemistry and insulin activity were measured. Subjects with a homeostasis model assessment-insulin resistance (HOMA-IR) level greater than the 75th percentile (> 2.25 for boys and > 2.89 for girls) were defined as insulin resistant. Non-obese boys with impaired insulin sensitivity had higher systolic blood pressure, lower HDL-cholesterol concentration, and fewer hours of vigorous exercise during weekdays, while non-obese girls with impaired insulin sensitivity had higher systolic blood pressure than their peers with normal insulin sensitivity. By multiple stepwise regression analysis, systolic blood pressure (p<0.001) and the hours of vigorous exercise during weekdays (p<0.03) were independently associated with HOMA-IR in boys, while systolic blood pressure (p<0.0001) and serum concentrations of HDL-cholesterol (p<0.01) were found in girls. In nonobese adolescents, insulin sensitivity is related with cardiovascular risk factors. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.72.3-4.161 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 72, 号 3-4, p. 161-166, 発行日 2010-08 |
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フォーマット | ||||||
application/pdf | ||||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/14178 | |||||
識別子タイプ | HDL |