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  1. B200 工学部/工学研究科
  2. B200a 雑誌掲載論文
  3. 学術雑誌

Optical pH Regulation Using Functional Nanotool Impregnating with Photo-Responsive Chemical for Intracellular Measurement

http://hdl.handle.net/2237/14484
http://hdl.handle.net/2237/14484
04e9e562-69ec-4ebd-bcaa-a7e95317baa7
名前 / ファイル ライセンス アクション
1086.pdf 1086.pdf (1.5 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2011-02-16
タイトル
タイトル Optical pH Regulation Using Functional Nanotool Impregnating with Photo-Responsive Chemical for Intracellular Measurement
言語 en
著者 Maruyama, Hisataka

× Maruyama, Hisataka

WEKO 39640

en Maruyama, Hisataka

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Masuda, Taisuke

× Masuda, Taisuke

WEKO 39641

en Masuda, Taisuke

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Inoue, Naoya

× Inoue, Naoya

WEKO 39642

en Inoue, Naoya

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Honda, Ayae

× Honda, Ayae

WEKO 39643

en Honda, Ayae

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Takahata, Tatsuro

× Takahata, Tatsuro

WEKO 39644

en Takahata, Tatsuro

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Arai, Fumihito

× Arai, Fumihito

WEKO 39645

en Arai, Fumihito

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
抄録
内容記述 We developed Optical pH regulation using functional nanotool impregnated with photo-responsive chemical for selective cell injection of nanotool. The nanotool was modified by fluorescent dye for intracellular measurement. The nanotool was included in the fusogenic liposome. Membrane fusion of the liposome to the cell membrane was used for invasive cell injection of the nanotool. The liposome fuses to the cell in weak acidic condition. Local pH regulation inside the liposome was developed using photochromic chemical for selective cell injection of the nanotool. The nanotool was modified by Leuco crystal violet (LCV). LCV emits the proton by ultraviolet (UV) illumination. The emitted proton decreases the pH value in the liposome. This pH regulation is reversible by UV/VIS illumination. The liposome was manipulated by optical tweezers. After contact of the liposome to the cell, the liposome was adhered to the cell by UV induced membrane fusion. Injected nanotool was manipulated by optical tweezers. Intracellular temperature was detected by measuring the fluorescence intensity of the nanosensor. We demonstrated optical pH regulation, selective cell injection of the nanotool, and manipulation of the nanotool in the cell.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 IEEE
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
ISBN
関連タイプ isPartOf
識別子タイプ ISBN
関連識別子 978-1-4244-7995-5
書誌情報 en : International Symposium on Micro-NanoMechatronics and Human Science (MHS)

p. 162-167, 発行日 2010
著者版フラグ
値 author
URI
識別子 http://hdl.handle.net/2237/14484
識別子タイプ HDL
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