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SUBTROCHANTERIC FRACTURE IN A PATIENT RECEIVING ZOLEDRONIC ACID THERAPY FOR METASTATIC BREAST CANCER
https://doi.org/10.18999/nagjms.73.3-4.211
https://doi.org/10.18999/nagjms.73.3-4.211abd4d72c-17d3-43cc-aff7-b926754d0a6e
名前 / ファイル | ライセンス | アクション |
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v73n34p211_215.pdf (485.1 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2011-08-25 | |||||
タイトル | ||||||
タイトル | SUBTROCHANTERIC FRACTURE IN A PATIENT RECEIVING ZOLEDRONIC ACID THERAPY FOR METASTATIC BREAST CANCER | |||||
言語 | en | |||||
著者 |
Kishimoto, Yasuzumi
× Kishimoto, Yasuzumi× Iwase, Toshiki× Koyama, Atsushi× Masui, Tetsuo× Yoshida, Go× Matsuo, Hideo× Ishiguro, Naoki |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bisphosphonate | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Zoledronic acid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Breast cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | SSBT | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Femoral fracture | |||||
抄録 | ||||||
内容記述 | A 61-year-old woman presented with acute pain of the right thigh after falling on a public street. She had been diagnosed with metastatic breast cancer and bisphosphonate therapy along with zoledronic acid. Radiographs demonstrated transverse subtrochanteric femoral fracture with thickening of the lateral cortex and spike of the medial cortex at the site of fracture. The contralateral femur showed thickening of the lateral cortex at the same site. This type of stress fracture is related to severe suppression of bone turnover (SSBT) under bisphosphonate therapy. Our patient had been receiving zoledronic acid therapy for 3.6 years, and the radiographic findings were typical of stress fracture associated with bisphosphonate. Therefore, the facture in our patient was considered related to SSBT under zoledronic acid therapy. Zoledronic acid is administered to patients with osteoporosis or complications due to cancer such as hypercalcemia of malignancy. Recently stress fractures associated with zoledronic acid therapy for osteoporosis have attracted attention. However, there are few reports of fracture associated with zoledronic acid therapy for cancer. Doses of zoledronic acid recommended for cancer patients are much greater than those for patients with osteoporosis. Clinicians treating such cancer patients need to cautiously manage stress fractures as a complication of zoledronic acid therapy. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.73.3-4.211 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 73, 号 3-4, p. 211-215, 発行日 2011-08 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/15364 | |||||
識別子タイプ | HDL |