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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 73(3-4)

SUBTROCHANTERIC FRACTURE IN A PATIENT RECEIVING ZOLEDRONIC ACID THERAPY FOR METASTATIC BREAST CANCER

https://doi.org/10.18999/nagjms.73.3-4.211
https://doi.org/10.18999/nagjms.73.3-4.211
abd4d72c-17d3-43cc-aff7-b926754d0a6e
名前 / ファイル ライセンス アクション
v73n34p211_215.pdf v73n34p211_215.pdf (485.1 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2011-08-25
タイトル
タイトル SUBTROCHANTERIC FRACTURE IN A PATIENT RECEIVING ZOLEDRONIC ACID THERAPY FOR METASTATIC BREAST CANCER
著者 Kishimoto, Yasuzumi

× Kishimoto, Yasuzumi

WEKO 42264

Kishimoto, Yasuzumi

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Iwase, Toshiki

× Iwase, Toshiki

WEKO 42265

Iwase, Toshiki

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Koyama, Atsushi

× Koyama, Atsushi

WEKO 42266

Koyama, Atsushi

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Masui, Tetsuo

× Masui, Tetsuo

WEKO 42267

Masui, Tetsuo

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Yoshida, Go

× Yoshida, Go

WEKO 42268

Yoshida, Go

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Matsuo, Hideo

× Matsuo, Hideo

WEKO 42269

Matsuo, Hideo

Search repository
Ishiguro, Naoki

× Ishiguro, Naoki

WEKO 42270

Ishiguro, Naoki

Search repository
キーワード
主題Scheme Other
主題 Bisphosphonate
キーワード
主題Scheme Other
主題 Zoledronic acid
キーワード
主題Scheme Other
主題 Breast cancer
キーワード
主題Scheme Other
主題 SSBT
キーワード
主題Scheme Other
主題 Femoral fracture
抄録
内容記述 A 61-year-old woman presented with acute pain of the right thigh after falling on a public street. She had been diagnosed with metastatic breast cancer and bisphosphonate therapy along with zoledronic acid. Radiographs demonstrated transverse subtrochanteric femoral fracture with thickening of the lateral cortex and spike of the medial cortex at the site of fracture. The contralateral femur showed thickening of the lateral cortex at the same site. This type of stress fracture is related to severe suppression of bone turnover (SSBT) under bisphosphonate therapy. Our patient had been receiving zoledronic acid therapy for 3.6 years, and the radiographic findings were typical of stress fracture associated with bisphosphonate. Therefore, the facture in our patient was considered related to SSBT under zoledronic acid therapy. Zoledronic acid is administered to patients with osteoporosis or complications due to cancer such as hypercalcemia of malignancy. Recently stress fractures associated with zoledronic acid therapy for osteoporosis have attracted attention. However, there are few reports of fracture associated with zoledronic acid therapy for cancer. Doses of zoledronic acid recommended for cancer patients are much greater than those for patients with osteoporosis. Clinicians treating such cancer patients need to cautiously manage stress fractures as a complication of zoledronic acid therapy.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.73.3-4.211
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 73, 号 3-4, p. 211-215, 発行日 2011-08
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/15364
識別子タイプ HDL
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