{"_buckets": {"deposit": "9185770e-7a05-46d1-8aed-73b48c59f2b3"}, "_deposit": {"id": "1379", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "1379"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00001379"}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2002-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1/2", "bibliographicPageEnd": "78", "bibliographicPageStart": "77", "bibliographicVolumeNumber": "46", "bibliographic_titles": [{"bibliographic_title": "Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University"}]}]}, "item_9_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "L-type Ca^\u003c2+\u003e channels (LTCCs) play essential roles in excitation and contraction. Four different ctj subunits (\u03b1_\u003c1S\u003e, \u03b1_\u003c1C\u003e, \u03b1_\u003c1D\u003e and\u03b1_\u003c1F\u003e) have been recoginized for the pore forming subunit of LTCC. We investigated mRNA expression of the four subunits in adultmouse heart (the left ventricle, the right appendage and the SA node region) using RT-PCR. \u03b1_\u003c1C\u003e mRNA was expressed in all examinedregions. \u03b1_\u003c1D\u003e mRNA was detected in sinoatrial (SA) node as well as in right atrium, but not in the ventricle. Expressions of \u03b1_\u003c1S\u003e and \u03b1_\u003c1F\u003emRNAs were below the level of detection at any sites. This observation suggests differential expression and different roles of LTCCscomposed of \u03b1_\u003c1C\u003e and \u03b1_\u003c1D\u003e subunits in the mammalian hearts.", "subitem_description_type": "Abstract"}]}, "item_9_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u56fd\u7acb\u60c5\u5831\u5b66\u7814\u7a76\u6240\u3067\u96fb\u5b50\u5316\u3057\u305f\u30b3\u30f3\u30c6\u30f3\u30c4\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u3002", "subitem_description_type": "Other"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/2789"}]}, "item_9_identifier_registration": {"attribute_name": "ID\u767b\u9332", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/envm.46.77", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Research Institute of Environmental Medicine, Nagoya University"}]}, "item_9_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "02870517", "subitem_source_identifier_type": "ISSN"}]}, "item_9_text_14": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "YASUI, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "3159", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "HOJO, Mayumi"}], "nameIdentifiers": [{"nameIdentifier": "3160", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "NIWA, Noriko"}], "nameIdentifiers": [{"nameIdentifier": "3161", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KODAMA, Itsuo"}], "nameIdentifiers": [{"nameIdentifier": "3162", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00000034869.pdf", "filesize": [{"value": "303.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 303900.0, "url": {"label": "KJ00000034869.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/1379/files/KJ00000034869.pdf"}, "version_id": "b28c6abb-ea22-4fc0-96ea-d22891e7801e"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "\u03b1_\u003c1C\u003e", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u03b1_\u003c1D\u003e", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Ca channel", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mouse", "subitem_subject_scheme": "Other"}, {"subitem_subject": "sinus node", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Regional Differences in Expression of L-type Ca^\u003c2+\u003e Channel \u03b1_1 Subunits in Mouse Heart", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Regional Differences in Expression of L-type Ca^\u003c2+\u003e Channel \u03b1_1 Subunits in Mouse Heart"}]}, "item_type_id": "9", "owner": "1", "path": ["329/333/334/335"], "permalink_uri": "https://doi.org/10.18999/envm.46.77", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2006-01-05"}, "publish_date": "2006-01-05", "publish_status": "0", "recid": "1379", "relation": {}, "relation_version_is_last": true, "title": ["Regional Differences in Expression of L-type Ca^\u003c2+\u003e Channel \u03b1_1 Subunits in Mouse Heart"], "weko_shared_id": null}