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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 56(1-4)

Evidence for Active Transport of 3H-Androgens Across the Epididymal Epithelium in the Rat

https://doi.org/10.18999/nagjms.56.1-4.111
https://doi.org/10.18999/nagjms.56.1-4.111
7c04fbeb-f995-4e31-8a9e-7c458dad7321
名前 / ファイル ライセンス アクション
v56n14p111_121.pdf v56n14p111_121.pdf (621.3 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-02-08
タイトル
タイトル Evidence for Active Transport of 3H-Androgens Across the Epididymal Epithelium in the Rat
著者 YAMAMOTO, MASANORI

× YAMAMOTO, MASANORI

WEKO 98841

YAMAMOTO, MASANORI

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TSUJI, YOSHIKAZU

× TSUJI, YOSHIKAZU

WEKO 98842

TSUJI, YOSHIKAZU

Search repository
MIYAKE, KOJI

× MIYAKE, KOJI

WEKO 98843

MIYAKE, KOJI

Search repository
キーワード
主題Scheme Other
主題 Active transport
キーワード
主題Scheme Other
主題 Androgen
キーワード
主題Scheme Other
主題 Epididymis
抄録
内容記述 The effect of metabolic inhibitors on transepithelial movement of 3H-androgens was investigated by in vivo perifusion and subsequent micropuncture of caput and cauda epididymal tubules. Epididymal tissue (adenosine triphosphate (ATP) concentrations were determined at 1 h after exposure of perifusion fluid with metabolic inhibitor. To determine whether or not metabolic inhibitor alters intraluminal androgen-binding protein concentration or androgen binding to interstitial proteins in the caput epididymis, 3H-dihydrotestosterone (DHT) binding to interaluminal androgen-binding protein and bound vs free androgen ratio in the interstitial fluid after 1 h perifusion with fluid containing metabolic inhibitor around caput epididymal tubules were examined. Proluminal movement of 3H-androgens and tissue ATP concentrations in the caput and cauda epididymis were significantly decreased by addition of dinitrophenol (DNP) or potassium cyanide to the perifusion fluid. Relative intraluminal androgen-binding protein protein concentration and bound vs free 3H-androgen ratio in the interstitial fluid were not altered when DNP or potassium cyanide was added to the perifusion fluid. These results demonstrate for the first time that an energy-dependent mechanism may be involved in the epididymal androgen uptake.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.56.1-4.111
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5614/5614.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 56, 号 1-4, p. 111-121, 発行日 1993-11-25
著者版フラグ
値 publisher
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