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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 57(1-2)

Intraluminal Content is Required for the Maintenance of Antigrade Proluminal Movement of 3H-Androgens into Rat Caput Epididymal Tubules

https://doi.org/10.18999/nagjms.57.1-2.77
https://doi.org/10.18999/nagjms.57.1-2.77
11496ae4-9724-4d99-a317-2d0c01ef72fe
名前 / ファイル ライセンス アクション
v57n12p77_83.pdf v57n12p77_83.pdf (469.7 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-02-13
タイトル
タイトル Intraluminal Content is Required for the Maintenance of Antigrade Proluminal Movement of 3H-Androgens into Rat Caput Epididymal Tubules
著者 YAMAMOTO, MASANORI

× YAMAMOTO, MASANORI

WEKO 98860

YAMAMOTO, MASANORI

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HIBI, HATSUKI

× HIBI, HATSUKI

WEKO 98861

HIBI, HATSUKI

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TSUJI, YOSHIKAZU

× TSUJI, YOSHIKAZU

WEKO 98862

TSUJI, YOSHIKAZU

Search repository
MIYAKE, KOJI

× MIYAKE, KOJI

WEKO 98863

MIYAKE, KOJI

Search repository
キーワード
主題Scheme Other
主題 Androgen-binding protein
キーワード
主題Scheme Other
主題 Androgen uptake
キーワード
主題Scheme Other
主題 Epididymis
抄録
内容記述 The present study was undertaken to determine whether or not antigrade, proluminal 3H-androgen movement in the caput epididymis occurs in the absence of native lumen content. A single tubule was perfused with artificial caput fluid containing no androgen-binding protein for 30 min and subsequently tubules were perifused with Minimum Essential Medium perifusion fluid containing 26.7 μCi/ml 3H-testosterone and 1.3 μCi/ml 14C-polyethyleneglycol for 1 h. Radioactivity of isotopes in perifusion and intraluminal fluids was determined at 1 h after sustaining perifusion, and the percentage of peritubular isotopes appearing in the intraluminal fluid was determined. Net entry of 3H-androgen into the epididymal tubules in the presence of native intraluminal content was approximately 323%. In contrast, intraluminal 3H-androgen concentrations in the epididymal fluid in the absence of native lumen content were significantly reduced, to 100% of those in the peritubular fluid. Antigrade, proluminal movement of 3H-androgen in the caput epididymis does not occur in the absence of native lumen content. Androgen-binding protein in the epididymal lumen may be required to maintain uphill proluminal movement of 3H-androgen into the tubules.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.57.1-2.77
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5712/5712.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 57, 号 1-2, p. 77-83, 発行日 1994-03-25
著者版フラグ
値 publisher
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