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Intraluminal Content is Required for the Maintenance of Antigrade Proluminal Movement of 3H-Androgens into Rat Caput Epididymal Tubules
https://doi.org/10.18999/nagjms.57.1-2.77
https://doi.org/10.18999/nagjms.57.1-2.7711496ae4-9724-4d99-a317-2d0c01ef72fe
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2012-02-13 | |||||
タイトル | ||||||
タイトル | Intraluminal Content is Required for the Maintenance of Antigrade Proluminal Movement of 3H-Androgens into Rat Caput Epididymal Tubules | |||||
著者 |
YAMAMOTO, MASANORI
× YAMAMOTO, MASANORI× HIBI, HATSUKI× TSUJI, YOSHIKAZU× MIYAKE, KOJI |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | Androgen-binding protein | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Androgen uptake | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Epididymis | |||||
抄録 | ||||||
内容記述 | The present study was undertaken to determine whether or not antigrade, proluminal 3H-androgen movement in the caput epididymis occurs in the absence of native lumen content. A single tubule was perfused with artificial caput fluid containing no androgen-binding protein for 30 min and subsequently tubules were perifused with Minimum Essential Medium perifusion fluid containing 26.7 μCi/ml 3H-testosterone and 1.3 μCi/ml 14C-polyethyleneglycol for 1 h. Radioactivity of isotopes in perifusion and intraluminal fluids was determined at 1 h after sustaining perifusion, and the percentage of peritubular isotopes appearing in the intraluminal fluid was determined. Net entry of 3H-androgen into the epididymal tubules in the presence of native intraluminal content was approximately 323%. In contrast, intraluminal 3H-androgen concentrations in the epididymal fluid in the absence of native lumen content were significantly reduced, to 100% of those in the peritubular fluid. Antigrade, proluminal movement of 3H-androgen in the caput epididymis does not occur in the absence of native lumen content. Androgen-binding protein in the epididymal lumen may be required to maintain uphill proluminal movement of 3H-androgen into the tubules. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.57.1-2.77 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5712/5712.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 57, 号 1-2, p. 77-83, 発行日 1994-03-25 |
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著者版フラグ | ||||||
値 | publisher |