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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 74(1-2)

RISK FACTORS FOR EXTENDED-SPECTRUM β-LACTAMASEPRODUCING ESCHERICHIA COLI INFECTION IN HOSPITALIZED PATIENTS

https://doi.org/10.18999/nagjms.74.1-2.105
https://doi.org/10.18999/nagjms.74.1-2.105
14ab8791-31b8-4a25-b686-aab1009f68ea
名前 / ファイル ライセンス アクション
10_Ikeda.pdf 10_Ikeda.pdf (362.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-02-29
タイトル
タイトル RISK FACTORS FOR EXTENDED-SPECTRUM β-LACTAMASEPRODUCING ESCHERICHIA COLI INFECTION IN HOSPITALIZED PATIENTS
著者 IKEDA, YOSHIAKI

× IKEDA, YOSHIAKI

WEKO 43920

IKEDA, YOSHIAKI

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MAMIYA, TAKAYOSHI

× MAMIYA, TAKAYOSHI

WEKO 43921

MAMIYA, TAKAYOSHI

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NISHIYAMA, HIDEKI

× NISHIYAMA, HIDEKI

WEKO 43922

NISHIYAMA, HIDEKI

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KOSEKI, TAKENAO

× KOSEKI, TAKENAO

WEKO 43923

KOSEKI, TAKENAO

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MOURI, AKIHIRO

× MOURI, AKIHIRO

WEKO 43924

MOURI, AKIHIRO

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NABESHIMA, TOSHITAKA

× NABESHIMA, TOSHITAKA

WEKO 43925

NABESHIMA, TOSHITAKA

Search repository
キーワード
主題Scheme Other
主題 Extended-spectrum
キーワード
主題Scheme Other
主題 β-lactamase
キーワード
主題Scheme Other
主題 ESBL
キーワード
主題Scheme Other
主題 Escherichia coli
キーワード
主題Scheme Other
主題 Risk factor
キーワード
主題Scheme Other
主題 Drug-resistant bacterium
抄録
内容記述 The incidence of nosocomial infection caused by extended-spectrum β-lactamase (ESBL)-producing bacteria is increasing worldwide. Infections caused by ESBL producers have been associated with severe adverse clinical outcomes that have led to increased mortality, prolonged hospitalization, and rising medical costs. To avoid such adverse events and ineffective treatment, an appropriate use of drugs for infectious diseases is needed. To suppress the emergence and spread of drug-resistant bacteria in hospitals, it is important to be vigilant about ESBL-producing Escherichia coli (E. coli). In this study, we examined and compared seven items in a blood test between patients with ESBL-producing E. coli and non- ESBL-producing E. coli among febrile patients. We examined the levels of serum albumin, hemoglobin, and C-reactive protein (CRP), and the numbers of leucocytes, neutrophils, lymphocytes, and platelets in blood on the day of admission, the screening day during hospitalization, and the day immediately before discharge from the hospital. There were no significant differences in clinical background characteristics between the two groups of patients. In patients with invasive infections caused by ESBL-producing E. coli, serum albumin levels and the number of lymphocytes were significantly lower than those in patients not infected with ESBL producers. These values recovered to their baseline levels on the day of hospital discharge. This retrospective study suggests that serum albumin levels and the number of lymphocytes may serve as risk factors for infection by ESBL-producing E. coli, thereby supporting the appropriate use of antimicrobials in hospitals.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.74.1-2.105
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 74, 号 1-2, p. 105-114, 発行日 2012-02
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7412/7412.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/16027
識別子タイプ HDL
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