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RISK FACTORS FOR EXTENDED-SPECTRUM β-LACTAMASEPRODUCING ESCHERICHIA COLI INFECTION IN HOSPITALIZED PATIENTS
https://doi.org/10.18999/nagjms.74.1-2.105
14ab8791-31b8-4a25-b686-aab1009f68ea
名前 / ファイル | ライセンス | アクション | |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2012-02-29 | |||||
タイトル | ||||||
タイトル | RISK FACTORS FOR EXTENDED-SPECTRUM β-LACTAMASEPRODUCING ESCHERICHIA COLI INFECTION IN HOSPITALIZED PATIENTS | |||||
著者 |
IKEDA, YOSHIAKI
× IKEDA, YOSHIAKI× MAMIYA, TAKAYOSHI× NISHIYAMA, HIDEKI× KOSEKI, TAKENAO× MOURI, AKIHIRO× NABESHIMA, TOSHITAKA |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | Extended-spectrum | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | β-lactamase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ESBL | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Escherichia coli | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Risk factor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Drug-resistant bacterium | |||||
抄録 | ||||||
内容記述 | The incidence of nosocomial infection caused by extended-spectrum β-lactamase (ESBL)-producing bacteria is increasing worldwide. Infections caused by ESBL producers have been associated with severe adverse clinical outcomes that have led to increased mortality, prolonged hospitalization, and rising medical costs. To avoid such adverse events and ineffective treatment, an appropriate use of drugs for infectious diseases is needed. To suppress the emergence and spread of drug-resistant bacteria in hospitals, it is important to be vigilant about ESBL-producing Escherichia coli (E. coli). In this study, we examined and compared seven items in a blood test between patients with ESBL-producing E. coli and non- ESBL-producing E. coli among febrile patients. We examined the levels of serum albumin, hemoglobin, and C-reactive protein (CRP), and the numbers of leucocytes, neutrophils, lymphocytes, and platelets in blood on the day of admission, the screening day during hospitalization, and the day immediately before discharge from the hospital. There were no significant differences in clinical background characteristics between the two groups of patients. In patients with invasive infections caused by ESBL-producing E. coli, serum albumin levels and the number of lymphocytes were significantly lower than those in patients not infected with ESBL producers. These values recovered to their baseline levels on the day of hospital discharge. This retrospective study suggests that serum albumin levels and the number of lymphocytes may serve as risk factors for infection by ESBL-producing E. coli, thereby supporting the appropriate use of antimicrobials in hospitals. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.74.1-2.105 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0027-7622 | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 74, 号 1-2, p. 105-114, 発行日 2012-02 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7412/7412.html | |||||
識別子タイプ | URI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/16027 | |||||
識別子タイプ | HDL |