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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 74(1-2)

PROGNOSTIC FACTORS FOR TUMOR RECURRENCE AFTER GAMMA KNIFE RADIOSURGERY OF PARTIALLY RESECTED AND RECURRENT CRANIOPHARYNGIOMAS

https://doi.org/10.18999/nagjms.74.1-2.141
https://doi.org/10.18999/nagjms.74.1-2.141
63a7b021-9c4b-44b3-af04-18b9126329e8
名前 / ファイル ライセンス アクション
14_Kobayashi.pdf 14_Kobayashi.pdf (85.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-03-01
タイトル
タイトル PROGNOSTIC FACTORS FOR TUMOR RECURRENCE AFTER GAMMA KNIFE RADIOSURGERY OF PARTIALLY RESECTED AND RECURRENT CRANIOPHARYNGIOMAS
著者 KOBAYASHI, TATSUYA

× KOBAYASHI, TATSUYA

WEKO 43946

KOBAYASHI, TATSUYA

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MORI, YOSHIMASA

× MORI, YOSHIMASA

WEKO 43947

MORI, YOSHIMASA

Search repository
TSUGAWA, TAKAHIKO

× TSUGAWA, TAKAHIKO

WEKO 43948

TSUGAWA, TAKAHIKO

Search repository
HASHIZUME, CHISA

× HASHIZUME, CHISA

WEKO 43949

HASHIZUME, CHISA

Search repository
TAKAHASHI, HIROSHI

× TAKAHASHI, HIROSHI

WEKO 43950

TAKAHASHI, HIROSHI

Search repository
キーワード
主題Scheme Other
主題 Prognostic factor
キーワード
主題Scheme Other
主題 Craniopharyngioma
キーワード
主題Scheme Other
主題 Recurrence
キーワード
主題Scheme Other
主題 Gamma knife radiosurgery
キーワード
主題Scheme Other
主題 Statistical analysis
抄録
内容記述 A study was conducted to clarify the prognostic factors related to recurrence of craniopharyngioma and to improve the quality of life of patients by the treatment with intentional partial removal and gamma knife radiosurgery. One hundred cases of craniopharyngioma have been treated at Komaki City Hospital since 1991. In a mean follow-up period of 65.5 months, the tumor control rate was 79.5%. The 5- and 10-year actuarial survival rates were 94.1% and 91%, respectively. However, the recurrence-free survival rates were 73.6% at 5 years and 60.2% at 10 years. Nine factors thought to be related to the recurrence were selected from past references and previous studies, including gender, age, pediatric (≤17 years) or adult patient, partial removal or recurrence, mean tumor diameter, tumor type (solid or cyst), pathological types (squamous cell or adamantinoma), number of previous treatments, and radiation dose. Statistical analysis was performed to determine which factors had a significant prognostic impact. Multivariate analysis showed that mean tumor diameter and radiation dose were independent predictors of outcome. To maximize the prognostic power of these factors, cut-off levels were determined using ROC analysis. These levels were 19 mm for tumor diameter and 13.2 Gy for marginal dose. Significant prognostic factors related to recurrence of craniopharyngioma are tumor diameter and radiation dose. A tumor diameter of <19 mm and a marginal dose of ≥13.2 Gy are favorable prognostic factors for gamma knife radiosurgery.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.74.1-2.141
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 74, 号 1-2, p. 141-147, 発行日 2012-02
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7412/7412.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/16031
識別子タイプ HDL
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