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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 59(3-4)

AN EXAMINATION OF THE CLOSE RELATIONSHIP BETWEEN LYMPHATIC VESSELS AND NERVE FIBERS CONTAINING CALCITONIN GENE-RELATED PEPTIDE AND SUBSTANCE P IN RAT SKIN

https://doi.org/10.18999/nagjms.59.3-4.143
https://doi.org/10.18999/nagjms.59.3-4.143
3c19e520-2697-4646-b20d-cfc048943306
名前 / ファイル ライセンス アクション
v59n34p143_150.pdf v59n34p143_150.pdf (1.8 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-03-27
タイトル
タイトル AN EXAMINATION OF THE CLOSE RELATIONSHIP BETWEEN LYMPHATIC VESSELS AND NERVE FIBERS CONTAINING CALCITONIN GENE-RELATED PEPTIDE AND SUBSTANCE P IN RAT SKIN
著者 YAMADA, KANSHO

× YAMADA, KANSHO

WEKO 44461

YAMADA, KANSHO

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HOSHINO, TAKESHI

× HOSHINO, TAKESHI

WEKO 44462

HOSHINO, TAKESHI

Search repository
キーワード
主題Scheme Other
主題 Neuropeptide-containing nerve fibers
キーワード
主題Scheme Other
主題 Lymphatic vessels
キーワード
主題Scheme Other
主題 Blood vessels
キーワード
主題Scheme Other
主題 Rat skin
キーワード
主題Scheme Other
主題 Immunohistochemistory
抄録
内容記述 The distribution of nerve fibers containing either calcitonin gene-related peptide (CGRP) and substance P (SP) was investigated in rat skin with special reference to their relationship to the lymphatic vessels. These nerve fibers exhibited a similar distribution pattern but the former were more numerous than the latter. In the dermis and subcutaneous layers, thin nerve fibers containing CGRP or SP were in abundance, and were observed running along the blood vessels as well as freely in the tissue. Nerve fibers with these peptides were often located close to lymphatic capillaries, and innervated lymphatic vessels in the subcutaneous layer, reaching smooth muscles of the tunica media. These findings suggest that some CGRP and SP may directly drain into lymphatic vessels when released under noxious stimulation from nerve fibers around the lymphatic vessels. When discharged from nerve fibers in the vicinity of blood vessels, both peptides may also drain into the lymphatic vessels after causing blood vascular dilation and an increase in permeability producing edema. These peptides may then be transported to the draining lymph nodes where they can modulate the functions of the immune system.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.59.3-4.143
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 59, 号 3-4, p. 143-150, 発行日 1996-12-27
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/16168
識別子タイプ HDL
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5934/5934.html
識別子タイプ URI
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