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  1. C100 医学部/医学系研究科
  2. C100d 学位論文
  3. 博士論文(医博・論医博)

Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia

http://hdl.handle.net/2237/16689
d3868bb0-db0a-4773-9ebd-379b6bfd2350
名前 / ファイル ライセンス アクション
o4230.pdf o4230.pdf (703.5 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2012-08-02
タイトル
タイトル Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia
著者 ASADA, Y

× ASADA, Y

WEKO 45565

ASADA, Y

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MIZUTANI, S

× MIZUTANI, S

WEKO 45566

MIZUTANI, S

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KASUGAI, M

× KASUGAI, M

WEKO 45567

KASUGAI, M

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KURAUCHI, O

× KURAUCHI, O

WEKO 45568

KURAUCHI, O

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TOMODA, Y

× TOMODA, Y

WEKO 45569

TOMODA, Y

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権利
権利情報 (C) Georg Thieme
キーワード
主題Scheme Other
主題 Systolic and Diastolic (S/D) Ratio of Maternal Uterine or Umbilical Artery
キーワード
主題Scheme Other
主題 Doppler Technique
キーワード
主題Scheme Other
主題 Pre-Eclampsia
キーワード
主題Scheme Other
主題 Placental Leucine Aminopeptidase (P-LAP)
キーワード
主題Scheme Other
主題 Aminopeptidase A
キーワード
主題Scheme Other
主題 Kininase I
キーワード
主題Scheme Other
主題 Vasoactive Peptides
キーワード
主題Scheme Other
主題 Utero-Placental Blood Flow Resistance
抄録
内容記述 Our study showed that there were statistically significant correlations between the systolic and diastolic ratio (S/D) of maternal uterine or umbilical artery and the levels of maternal serum aminopeptidase activities in pre-eclampsia. Kininase I was positively correlated with the S/D ratios, whereas placental leucine aminopeptidase (P-LAP) and aminopeptidase A were negatively correlated with the S/D ratios. It is known that the increased S/D ratios reflect the increased utero-placental blood flow resistance. Since our previous study showed that placental aminopeptidases degrade vasoactive peptides such as oxytocin, angiotensin and bradykinin, which the fetus actively produces, our present study suggests that the increased vascular resistance in feto-placental circulation in pre-eclampsia is partly controlled by changes in vaso-active peptides, via degradation by placental aminopeptidases.
内容記述タイプ Abstract
内容記述
内容記述 名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成4年7月20日 淺田義正氏の博士論文として提出された
内容記述タイプ Other
出版者
出版者 Georg Thieme
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_46ec
タイプ thesis
ISSN
収録物識別子タイプ ISSN
収録物識別子 0018-5043
書誌情報 Hormone and Metabolic Research

巻 24, 号 7, p. 342-344, 発行日 1992-07
学位授与年度
学位授与年度 1992
学位授与年月日
学位授与年月日 1992-07-01
学位授与番号
学位授与番号 13901乙第4230号
著者版フラグ
値 publisher
URI
識別子 http://dx.doi.org/10.1055/s-2007-1003329
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/16689
識別子タイプ HDL
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