{"_buckets": {"deposit": "eaba6bb4-14b5-440b-bf4c-5675e1ac26fa"}, "_deposit": {"id": "14762", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "14762"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00014762"}, "item_12_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1992-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "344", "bibliographicPageStart": "342", "bibliographicVolumeNumber": "24", "bibliographic_titles": [{"bibliographic_title": "Hormone and Metabolic Research"}]}]}, "item_12_date_granted_64": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5", "attribute_value_mlt": [{"subitem_dategranted": "1992-07-01"}]}, "item_12_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Our study showed that there were statistically significant correlations between the systolic and diastolic ratio (S/D) of maternal uterine or umbilical artery and the levels of maternal serum aminopeptidase activities in pre-eclampsia. Kininase I was positively correlated with the S/D ratios, whereas placental leucine aminopeptidase (P-LAP) and aminopeptidase A were negatively correlated with the S/D ratios. It is known that the increased S/D ratios reflect the increased utero-placental blood flow resistance. Since our previous study showed that placental aminopeptidases degrade vasoactive peptides such as oxytocin, angiotensin and bradykinin, which the fetus actively produces, our present study suggests that the increased vascular resistance in feto-placental circulation in pre-eclampsia is partly controlled by changes in vaso-active peptides, via degradation by placental aminopeptidases.", "subitem_description_type": "Abstract"}]}, "item_12_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u540d\u53e4\u5c4b\u5927\u5b66\u535a\u58eb\u5b66\u4f4d\u8ad6\u6587 \u5b66\u4f4d\u306e\u7a2e\u985e : \u535a\u58eb(\u533b\u5b66)(\u8ad6\u6587) \u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5:\u5e73\u62104\u5e747\u670820\u65e5 \u6dfa\u7530\u7fa9\u6b63\u6c0f\u306e\u535a\u58eb\u8ad6\u6587\u3068\u3057\u3066\u63d0\u51fa\u3055\u308c\u305f", "subitem_description_type": "Other"}]}, "item_12_dissertation_number_65": {"attribute_name": 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{"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u5e74\u5ea6", "attribute_value_mlt": [{"subitem_text_value": "1992"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "ASADA, Y"}], "nameIdentifiers": [{"nameIdentifier": "45565", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "MIZUTANI, S"}], "nameIdentifiers": [{"nameIdentifier": "45566", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KASUGAI, M"}], "nameIdentifiers": [{"nameIdentifier": "45567", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KURAUCHI, O"}], "nameIdentifiers": [{"nameIdentifier": "45568", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TOMODA, Y"}], "nameIdentifiers": [{"nameIdentifier": "45569", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "o4230.pdf", "filesize": [{"value": "703.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 703500.0, "url": {"label": "o4230.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/14762/files/o4230.pdf"}, "version_id": "5b5542ca-4e47-4d24-a032-e232af128d93"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Systolic and Diastolic (S/D) Ratio of Maternal Uterine or Umbilical Artery", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Doppler Technique", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Pre-Eclampsia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Placental Leucine Aminopeptidase (P-LAP)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Aminopeptidase A", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Kininase I", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Vasoactive Peptides", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Utero-Placental Blood Flow Resistance", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia"}]}, "item_type_id": "12", "owner": "1", "path": ["499/960/1165"], "permalink_uri": "http://hdl.handle.net/2237/16689", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2012-08-02"}, "publish_date": "2012-08-02", "publish_status": "0", "recid": "14762", "relation": {}, "relation_version_is_last": true, "title": ["Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia"], "weko_shared_id": null}