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Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia
http://hdl.handle.net/2237/16689
http://hdl.handle.net/2237/16689d3868bb0-db0a-4773-9ebd-379b6bfd2350
名前 / ファイル | ライセンス | アクション |
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o4230.pdf (703.5 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2012-08-02 | |||||
タイトル | ||||||
タイトル | Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia | |||||
言語 | en | |||||
著者 |
ASADA, Y
× ASADA, Y× MIZUTANI, S× KASUGAI, M× KURAUCHI, O× TOMODA, Y |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | (C) Georg Thieme | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Systolic and Diastolic (S/D) Ratio of Maternal Uterine or Umbilical Artery | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Doppler Technique | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pre-Eclampsia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Placental Leucine Aminopeptidase (P-LAP) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Aminopeptidase A | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Kininase I | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Vasoactive Peptides | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Utero-Placental Blood Flow Resistance | |||||
抄録 | ||||||
内容記述 | Our study showed that there were statistically significant correlations between the systolic and diastolic ratio (S/D) of maternal uterine or umbilical artery and the levels of maternal serum aminopeptidase activities in pre-eclampsia. Kininase I was positively correlated with the S/D ratios, whereas placental leucine aminopeptidase (P-LAP) and aminopeptidase A were negatively correlated with the S/D ratios. It is known that the increased S/D ratios reflect the increased utero-placental blood flow resistance. Since our previous study showed that placental aminopeptidases degrade vasoactive peptides such as oxytocin, angiotensin and bradykinin, which the fetus actively produces, our present study suggests that the increased vascular resistance in feto-placental circulation in pre-eclampsia is partly controlled by changes in vaso-active peptides, via degradation by placental aminopeptidases. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | 名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成4年7月20日 淺田義正氏の博士論文として提出された | |||||
言語 | ja | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Georg Thieme | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||
タイプ | doctoral thesis | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1055/s-2007-1003329 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0018-5043 | |||||
書誌情報 |
en : Hormone and Metabolic Research 巻 24, 号 7, p. 342-344, 発行日 1992-07 |
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学位名 | ||||||
言語 | ja | |||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 13901 | |||||
言語 | ja | |||||
学位授与機関名 | 名古屋大学 | |||||
言語 | en | |||||
学位授与機関名 | NAGOYA University | |||||
学位授与年度 | ||||||
学位授与年度 | 1992 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 1992-07-01 | |||||
学位授与番号 | ||||||
学位授与番号 | 乙第4230号 | |||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://dx.doi.org/10.1055/s-2007-1003329 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/16689 | |||||
識別子タイプ | HDL |