{"_buckets": {"deposit": "eaba6bb4-14b5-440b-bf4c-5675e1ac26fa"}, "_deposit": {"id": "14762", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "14762"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00014762", "sets": ["1165"]}, "author_link": ["45565", "45566", "45567", "45568", "45569"], "item_12_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1992-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "344", "bibliographicPageStart": "342", "bibliographicVolumeNumber": "24", "bibliographic_titles": [{"bibliographic_title": "Hormone and Metabolic Research", "bibliographic_titleLang": "en"}]}]}, "item_12_date_granted_64": {"attribute_name": "学位授与年月日", "attribute_value_mlt": [{"subitem_dategranted": "1992-07-01"}]}, "item_12_degree_grantor_62": {"attribute_name": "学位授与機関", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_language": "ja", "subitem_degreegrantor_name": "名古屋大学"}, {"subitem_degreegrantor_language": "en", "subitem_degreegrantor_name": "NAGOYA University"}], "subitem_degreegrantor_identifier": [{"subitem_degreegrantor_identifier_name": "13901", "subitem_degreegrantor_identifier_scheme": "kakenhi"}]}]}, "item_12_degree_name_61": {"attribute_name": "学位名", "attribute_value_mlt": [{"subitem_degreename": "博士(医学)", "subitem_degreename_language": "ja"}]}, "item_12_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Our study showed that there were statistically significant correlations between the systolic and diastolic ratio (S/D) of maternal uterine or umbilical artery and the levels of maternal serum aminopeptidase activities in pre-eclampsia. Kininase I was positively correlated with the S/D ratios, whereas placental leucine aminopeptidase (P-LAP) and aminopeptidase A were negatively correlated with the S/D ratios. It is known that the increased S/D ratios reflect the increased utero-placental blood flow resistance. Since our previous study showed that placental aminopeptidases degrade vasoactive peptides such as oxytocin, angiotensin and bradykinin, which the fetus actively produces, our present study suggests that the increased vascular resistance in feto-placental circulation in pre-eclampsia is partly controlled by changes in vaso-active peptides, via degradation by placental aminopeptidases.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_12_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成4年7月20日 淺田義正氏の博士論文として提出された", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_12_dissertation_number_65": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "乙第4230号"}]}, "item_12_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://dx.doi.org/10.1055/s-2007-1003329"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/16689"}]}, "item_12_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Georg Thieme", "subitem_publisher_language": "en"}]}, "item_12_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1055/s-2007-1003329", "subitem_relation_type_select": "DOI"}}]}, "item_12_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "(C) Georg Thieme", "subitem_rights_language": "en"}]}, "item_12_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_12_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0018-5043", "subitem_source_identifier_type": "PISSN"}]}, "item_12_text_63": {"attribute_name": "学位授与年度", "attribute_value_mlt": [{"subitem_text_value": "1992"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "ASADA, Y", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "45565", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "MIZUTANI, S", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "45566", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KASUGAI, M", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "45567", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KURAUCHI, O", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "45568", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TOMODA, Y", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "45569", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "o4230.pdf", "filesize": [{"value": "703.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 703500.0, "url": {"label": "o4230.pdf", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/14762/files/o4230.pdf"}, "version_id": "5b5542ca-4e47-4d24-a032-e232af128d93"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Systolic and Diastolic (S/D) Ratio of Maternal Uterine or Umbilical Artery", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Doppler Technique", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Pre-Eclampsia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Placental Leucine Aminopeptidase (P-LAP)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Aminopeptidase A", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Kininase I", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Vasoactive Peptides", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Utero-Placental Blood Flow Resistance", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_title": "Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia", "subitem_title_language": "en"}]}, "item_type_id": "12", "owner": "1", "path": ["1165"], "permalink_uri": "http://hdl.handle.net/2237/16689", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2012-08-02"}, "publish_date": "2012-08-02", "publish_status": "0", "recid": "14762", "relation": {}, "relation_version_is_last": true, "title": ["Relationship Between the Changes in Placental Blood Flow Resistance Assessed by Doppler Technique and Maternal Serum Placental Aminopeptidases, which Degrade Vaso-Active Peptides, in Pre-Eclampsia"], "weko_shared_id": -1}