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Clinical results of nonsurgical treatment for spinal metastases
http://hdl.handle.net/2237/16692
http://hdl.handle.net/2237/166926bbd4f1c-b735-481f-a03a-7e5efc2a7a30
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
o5522.pdf (1.3 MB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2012-08-06 | |||||
| タイトル | ||||||
| タイトル | Clinical results of nonsurgical treatment for spinal metastases | |||||
| 言語 | en | |||||
| 著者 |
Katagiri, Hirohisa
× Katagiri, Hirohisa× Takahashi, Mitsuru× Inagaki, Jiro× Kobayashi, Hidetoshi× Sugiura, Hideshi× Yamamura, Shigeki× Iwata, Hisashi |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 権利 | ||||||
| 言語 | en | |||||
| 権利情報 | This is the author's version of a work that was accepted for publication in International Journal of Radiation Oncology・Biology・Physics. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms, may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in International Journal of Radiation Oncology・Biology・Physics. v.42, n.5, 1998, p.1127–1132 http://dx.doi.org/10.1016/S0360-3016(98)00288-0 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Spinal metastasis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Neurological status | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Survival | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Radiation therapy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Chemotherapy | |||||
| 抄録 | ||||||
| 内容記述 | Purpose: In contrast with many analyses of surgical treatment for spinal metastases, there have been only a few recent well-documented publications assessing nonsurgical treatment. This paper is a study of the outcome of nonsurgical therapy for metastatic tumors of the spine. Methods and Materials: One hundred and one patients with spinal metastases were treated with radiation therapy and/or chemotherapy without surgical intervention between 1990 and 1995, in prospective analysis, and had follow-up for more than 24 months. This study included 59 men and 42 women with a mean age of 61 years (range: 14 to 81). Mean follow-up periods were 11 months for patients dying of the disease and 53 months for the survivors. Neurological status, pain relief, functional improvement, and cumulative survival rate were assessed. Results: Of the total treated, 67 patients (66%) were evaluated as being neurologically stable or improved after treatment. Pain relief was achieved in 67%, and 64% showed functional improvement. Primary lesion responsiveness to nonsurgical therapy influenced the survival, neurological recovery, pain control, and function. Neurological findings before therapy were useful in predicting ambulatory status after treatment. Conclusion: Nonsurgical treatment was often successful when primary tumors had responsiveness to radiation therapy and/or chemotherapy. We found this to be evident even when neurological deficits were found, particularly in lumbar spines. Spinal metastases of tumors with less responsiveness, unless patients were neurologically intact, responded poorly to therapy. Most of the patients who were successfully treated enjoyed relief lasting nearly until death. Their functional ability was limited by general debility, rather than by local tumor regeneration. | |||||
| 言語 | en | |||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | ||||||
| 内容記述 | 名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成11年1月22日 片桐浩久氏の博士論文として提出された | |||||
| 言語 | ja | |||||
| 内容記述タイプ | Other | |||||
| 出版者 | ||||||
| 言語 | en | |||||
| 出版者 | Elsevier | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_db06 | |||||
| タイプ | doctoral thesis | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1016/S0360-3016(98)00288-0 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0360-3016 | |||||
| 書誌情報 |
en : International Journal of Radiation Oncology・Biology・Physics 巻 42, 号 5, p. 1127-1132, 発行日 1998-12-01 |
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| 学位名 | ||||||
| 言語 | ja | |||||
| 学位名 | 博士(医学) | |||||
| 学位授与機関 | ||||||
| 学位授与機関識別子Scheme | kakenhi | |||||
| 学位授与機関識別子 | 13901 | |||||
| 言語 | ja | |||||
| 学位授与機関名 | 名古屋大学 | |||||
| 言語 | en | |||||
| 学位授与機関名 | NAGOYA University | |||||
| 学位授与年度 | ||||||
| 学位授与年度 | 1998 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 1998-12-01 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 乙第5522号 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://dx.doi.org/10.1016/S0360-3016(98)00288-0 | |||||
| 識別子タイプ | DOI | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/16692 | |||||
| 識別子タイプ | HDL | |||||
