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  1. C100 医学部/医学系研究科
  2. C100d 学位論文
  3. 博士論文(医博・論医博)

Differing effects of vasopressin on regional cerebral blood flow of dogs following intracisternal vs. intra-arterial administration

http://hdl.handle.net/2237/16721
http://hdl.handle.net/2237/16721
cc029f39-4283-4f9a-9539-c7aecf3b9323
名前 / ファイル ライセンス アクション
k3020.pdf k3020.pdf (709.2 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2012-08-22
タイトル
タイトル Differing effects of vasopressin on regional cerebral blood flow of dogs following intracisternal vs. intra-arterial administration
言語 en
著者 Tsugane, Shinichiro

× Tsugane, Shinichiro

WEKO 45677

en Tsugane, Shinichiro

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Suzuki, Yoshio

× Suzuki, Yoshio

WEKO 45678

en Suzuki, Yoshio

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Kano, Takahisa

× Kano, Takahisa

WEKO 45679

en Kano, Takahisa

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Takayasu, Masakazu

× Takayasu, Masakazu

WEKO 45680

en Takayasu, Masakazu

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Shibuya, Masato

× Shibuya, Masato

WEKO 45681

en Shibuya, Masato

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Sugita, Kenichiro

× Sugita, Kenichiro

WEKO 45682

en Sugita, Kenichiro

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 This is the author's version of a work that was accepted for publication in Life Sciences. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms, may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Life Sciences. v.54, n.15, 1994, p.PL241–PL246 http://dx.doi.org/10.1016/0024-3205(94)00424-2
抄録
内容記述 We investigated the differential effect of the intracisternal and intraarterial administration of vasopressin on the regional cerebral blood flow (rCBF) in the parietal cortex of dogs. Regional CBF, velocity and blood volume were assayed by laser flowmetry. The intracisternal injection of 1 nmol vasopressin significantly increased the rCBF and velocity, without affecting blood volume. However, the intravertebral arterial injection of 1 nmol vasopressin significantly decreased the rCBF and velocity. This discrepancy can be explained by a difference in the affected vasculature; large blood vessels in the subarachnoid space vs. whole cerebral vascular system. The intracisternal and intraarterial injection of the nitric oxide inhibitor NG-monomethyl-L-arginine reduced the rCBF from the base line, and significantly suppressed the rCBF elevation induced by vasopressin. The effect of vasopressin may be considered as the summation of the increased flow from the dilated large vessels via the release of nitric oxide from the endothelium, and of the decreased flow from the contracted small vessels.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 名古屋大学博士学位論文 学位の種類 : 博士(医学)(課程) 学位授与年月日:平成6年3月25日 津金慎一郎氏の博士論文として提出された
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Elsevier
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_db06
タイプ doctoral thesis
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/0024-3205(94)00424-2
ISSN
収録物識別子タイプ PISSN
収録物識別子 0024-3205
書誌情報 en : Life Sciences

巻 54, 号 15, p. PL241-PL246, 発行日 1994
学位名
言語 ja
学位名 博士(医学)
学位授与機関
学位授与機関識別子Scheme kakenhi
学位授与機関識別子 13901
言語 ja
学位授与機関名 名古屋大学
言語 en
学位授与機関名 NAGOYA University
学位授与年度
学位授与年度 1993
学位授与年月日
学位授与年月日 1994-01-01
学位授与番号
学位授与番号 甲第3020号
著者版フラグ
値 publisher
URI
識別子 http://dx.doi.org/10.1016/0024-3205(94)00424-2
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/16721
識別子タイプ HDL
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