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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 63(1-2)

Cell Biology of Caveolae and Its Implication for Clinical Medicine

https://doi.org/10.18999/nagjms.63.1-2.9
https://doi.org/10.18999/nagjms.63.1-2.9
a00f6a9d-da69-46a1-a865-961046084e3d
名前 / ファイル ライセンス アクション
v63n12p9_18.pdf v63n12p9_18.pdf (1.3 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-08-30
タイトル
タイトル Cell Biology of Caveolae and Its Implication for Clinical Medicine
著者 FUJIMOTO, TOYOSHI

× FUJIMOTO, TOYOSHI

WEKO 45841

FUJIMOTO, TOYOSHI

Search repository
キーワード
主題Scheme Other
主題 caveolae
キーワード
主題Scheme Other
主題 caveolin
キーワード
主題Scheme Other
主題 raft
キーワード
主題Scheme Other
主題 signal transduction
キーワード
主題Scheme Other
主題 cholesterol
抄録
内容記述 Caveolae are small invaginations of the plasma membrane found in many cell types, and caveolins are integral membrane proteins that form the framework of caveolae. In the past several years, research on caveolae has developed explosively, and caveolae and/or caveolins have been shown to play many important roles in cell physiology: in particular, they are thought to be related to signal transduction, cholesterol transport, endocytosis and tumor suppression. On the other hand, some studies have suggested that another membrane domain called rafts is also involved in the same processes, and some confusion remains concerning the relationship between these two domains. Abnormalities in caveolae and/or caveolins have been found in various diseases, including cancer, atherosclerosis, muscular dystrophy and the Alzheimer's disease, which may make this domain a new focus for pharmacological research. This review will focus on the cell biology of caveolae, caveolins and rafts, and then summarize the implications of these findings for clinical studies.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.63.1-2.9
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 63, 号 1-2, p. 9-18, 発行日 2000-05
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/6312/6312.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/16761
識別子タイプ HDL
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