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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 36(2-4)

Regional Intravascular Chemotherapy for Experimental Liver Metastasis

https://doi.org/10.18999/nagjms.36.2-4.63
https://doi.org/10.18999/nagjms.36.2-4.63
46d004ce-cc8d-4f2c-99f5-83b541539ac4
名前 / ファイル ライセンス アクション
v36n24p63_69.pdf v36n24p63_69.pdf (1.5 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-01-18
タイトル
タイトル Regional Intravascular Chemotherapy for Experimental Liver Metastasis
著者 ICHIHASHI, HIDEHITO

× ICHIHASHI, HIDEHITO

WEKO 46614

ICHIHASHI, HIDEHITO

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HISAZAKI, MAYUKI

× HISAZAKI, MAYUKI

WEKO 46615

HISAZAKI, MAYUKI

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YASUE, MANJI

× YASUE, MANJI

WEKO 46616

YASUE, MANJI

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KONDO, TATSUHEI

× KONDO, TATSUHEI

WEKO 46617

KONDO, TATSUHEI

Search repository
抄録
内容記述 To investigate the effectiveness of intravascular chemotherapy, the rats implanted with two different sizes and ages of Yoshida sarcoma into the liver were treated with Mitomycin-C through either the hepatic artery or the portal vein. The administration of Mitomycin-C was effective by both arterial and portal routes on the rats bearing small young tumor, whereas it was effective only by arterial route on the rats bearing large developed tumor. Tumor regression was also observed on the rats bearing the tumor after ligation of the hepatic artery. Further, to observe the relationship between tumor growth and its blood supply, microangiography was performed by injection of AgI colloid through the hepatic artery and the portal vein. The branches of the hepatic artery flourished around the tumor at the 4th day after implantation and gradually entered into the tumor area at the 6th day. Thereafter, tumor area was occupied by the arterial branches and later the branches were occluded by the progressive growth of tumor. On the other hand, the branches of the portal vein were obliterated earlier than those of the hepatic artery and at the 5th day no branches were observed in the tumor area. These vascular changes are closely related to tumor growth, so that special regard should be paid to the change of the blood supply when chemotherapeutic agents are given.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.36.2-4.63
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 36, 号 2-4, p. 63-69, 発行日 1974-03
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/3624/3624.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17290
識別子タイプ HDL
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