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Significant Role of Intrahepatic Shunt in Hepatic Function Test with the Use of Dye in Cirrhosis
https://doi.org/10.18999/nagjms.41.1-4.1
https://doi.org/10.18999/nagjms.41.1-4.10d29298e-c8fb-48c3-bb44-4fba350636df
名前 / ファイル | ライセンス | アクション |
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v41n14p1_8.pdf (606.7 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-01-23 | |||||
タイトル | ||||||
タイトル | Significant Role of Intrahepatic Shunt in Hepatic Function Test with the Use of Dye in Cirrhosis | |||||
言語 | en | |||||
著者 |
HORISAWA, MASUMASA
× HORISAWA, MASUMASA |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
抄録 | ||||||
内容記述 | Using hepatic vein catheterization, fractional clearance (K) and hepatic extraction rate (ER) of Indocyanine Green (ICG) and radioisotope particles (RI) were studied in cirrhotic portal hypertension (24 postnecrotic cirrhotics and 25 alcoholic cirrhotics). ICG given intravenously is cleared from blood only by hepatocytes, whereas RI are uptaken by intrahepatic (Kupffer cells) and extrahepatic reticuloendothelial (RE) cells. Since there were significant positive correlations between K-ICG and K-RI in postnecrotic cirrhosis (r = 0.588, p < 0.01) and in alcoholic cirrhosis (r = 0.620, p < 0.01), and between ER-ICG and ER-RI in postnecrotic cirrhosis (r =0.508, p < 0.02) and in alcoholic cirrhosis (r = 0.558, p < 0.01), the most reasonable explanation of these correlations was that significant amount of ICG and Rl given intravenously bypassed both Kupffer cells and hepatocytes in the patients with portal hypertenaion due to cirrhosis. Therefore, liver function test with the use of dye, such as ICG, is influenced significantly by intrahepatic shunt bypassing hepatocytes in cirrhosis. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.41.1-4.1 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4114/4114.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 41, 号 1-4, p. 1-8, 発行日 1979-03 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/17357 | |||||
識別子タイプ | HDL |