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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 43(3-4)

Glomerular Basement Membrane Thickening in Renal Allografts

https://doi.org/10.18999/nagjms.43.3-4.71
https://doi.org/10.18999/nagjms.43.3-4.71
a3c69cb1-8d01-4b38-af95-14a9a46570a7
名前 / ファイル ライセンス アクション
v43n34p71_88.pdf v43n34p71_88.pdf (4.1 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-01-24
タイトル
タイトル Glomerular Basement Membrane Thickening in Renal Allografts
著者 WAKABAYASHI, TOMO

× WAKABAYASHI, TOMO

WEKO 46829

WAKABAYASHI, TOMO

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キーワード
主題Scheme Other
主題 Transplanted kindney
キーワード
主題Scheme Other
主題 glomerular basement membrane
キーワード
主題Scheme Other
主題 Mesangiolysis
キーワード
主題Scheme Other
主題 Transplant glomerulopathy
キーワード
主題Scheme Other
主題 Rejection
抄録
内容記述 Diffuse thickening of glomerular basement membranes (GBM) was optically observed in the renal grafts of 15 patients (21 specimens) among 70 recipients (128 specimens). Most of these specimens with diffuse GBM thickening were examined ultrastructurally. All cases with the above change were only found in allografts. The correlation was observed between the degree of GBM thickening and the clinical course, which can be classified into 3 groups. Group I showed a marked thickening of subendothelial spaces of GBM due to the accumulation of electron-lucent material. The cases of Group I fell into renal failure within relatively short periods because of either continued or repeated acute rejections (4 cases at 10 weeks to 15 months after transplantation). Group II showed a relatively mild thickening of subendothelial spaces and mild thickening of laminae densae accompanied by chronic rejections (7 cases at 9 months to 10 years and 10 months after transplantation). Group III showed glomerulonephritis-like changes and chronic clinical courses (3 cases with membranoproliferative glomerulonephritis (MPGN)-like change and one case with membranous nephropathy (MN)-like change). The GBM thickening was milder in Group II than in Group I. Mesangiolysis was found in both groups, which was, however, milder in Group II. The one case with MN-like change in Group III was considered to be complicated with MN under chronic rejection. As to the 3 cases with MPGN-like changes in Group III, it can not be concluded at a preset, whether they are to be attributed to a special form of chronic rejection itself or to a chronic rejection on which glomerulonephritis or some other factor(s) may be superimposed.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.43.3-4.71
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 43, 号 3-4, p. 71-88, 発行日 1981-03
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4334/4334.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17384
識別子タイプ HDL
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