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The Clinical Investigation of 1α-OH-D3 on Hemodialized Patients
https://doi.org/10.18999/nagjms.44.3-4.89
https://doi.org/10.18999/nagjms.44.3-4.89fbe2f9d9-77b8-4e2f-b03d-159095d3ca6e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
v44n34p89_101.pdf (818.2 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-01-25 | |||||
| タイトル | ||||||
| タイトル | The Clinical Investigation of 1α-OH-D3 on Hemodialized Patients | |||||
| 言語 | en | |||||
| 著者 |
WATANABE, YUZO
× WATANABE, YUZO× ASAI, KANlCHI× OKURA, TAKANOBU× KAWAHARA, HlROHlSA× SAKAMOTO, NOBUO |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 1α-OH-D3 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | renal | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | osteodystrophy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | secondary | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | hyperparathyroidism | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | hemodialysis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | calcium lactate | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The clinical effect of 1α-OH-D3, a synthetic analogue of the active form of Vitamin D, was investigated in hemodialized patients. The administration of 1α-OH-D3 with supplementary calcium therapy (at doses equivalent to 520 mg of elemental calcium per day) produced a significant biochemical improvement characterized by an increase in serum calcium concentration, lowered serum inorganic phosphate content and diminution of(Ca)X(Pi), without any appreciable increase in parathyroid hormone (PTH). There was actually no patient showing exacerbation in skeletal X-ray findings following the treatment. The reversal from a lowered serum calcium level might be largely ascribable to the improvement of the alimentary balance of calcium. Also, the decrease in serum inorganic phosphate value might have been brought about by the suppression of phosphorus absorption by supplementary calcium lactate administraion, by phosphorus deposition in bones, and by suppression of bone resorption by PTH. It was found that a calcium concentration of 3.5 mEq / L approx, in the dialysate was adequate for periodic hemodialysis. The data indicated the effectiveness of the administration of 1α-OH-D3 with calcium supplementation for the prevention and treatment of renal osteodystrophy in the maintenance of hemodialized patients. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.44.3-4.89 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4434/4434.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 44, 号 3-4, p. 89-101, 発行日 1982-03 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/17400 | |||||
| 識別子タイプ | HDL | |||||
