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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 44(3-4)

The Clinical Investigation of 1α-OH-D3 on Hemodialized Patients

https://doi.org/10.18999/nagjms.44.3-4.89
https://doi.org/10.18999/nagjms.44.3-4.89
fbe2f9d9-77b8-4e2f-b03d-159095d3ca6e
名前 / ファイル ライセンス アクション
v44n34p89_101.pdf v44n34p89_101.pdf (818.2 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-01-25
タイトル
タイトル The Clinical Investigation of 1α-OH-D3 on Hemodialized Patients
著者 WATANABE, YUZO

× WATANABE, YUZO

WEKO 46885

WATANABE, YUZO

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ASAI, KANlCHI

× ASAI, KANlCHI

WEKO 46886

ASAI, KANlCHI

Search repository
OKURA, TAKANOBU

× OKURA, TAKANOBU

WEKO 46887

OKURA, TAKANOBU

Search repository
KAWAHARA, HlROHlSA

× KAWAHARA, HlROHlSA

WEKO 46888

KAWAHARA, HlROHlSA

Search repository
SAKAMOTO, NOBUO

× SAKAMOTO, NOBUO

WEKO 46889

SAKAMOTO, NOBUO

Search repository
キーワード
主題Scheme Other
主題 1α-OH-D3
キーワード
主題Scheme Other
主題 renal
キーワード
主題Scheme Other
主題 osteodystrophy
キーワード
主題Scheme Other
主題 secondary
キーワード
主題Scheme Other
主題 hyperparathyroidism
キーワード
主題Scheme Other
主題 hemodialysis
キーワード
主題Scheme Other
主題 calcium lactate
抄録
内容記述 The clinical effect of 1α-OH-D3, a synthetic analogue of the active form of Vitamin D, was investigated in hemodialized patients. The administration of 1α-OH-D3 with supplementary calcium therapy (at doses equivalent to 520 mg of elemental calcium per day) produced a significant biochemical improvement characterized by an increase in serum calcium concentration, lowered serum inorganic phosphate content and diminution of(Ca)X(Pi), without any appreciable increase in parathyroid hormone (PTH). There was actually no patient showing exacerbation in skeletal X-ray findings following the treatment. The reversal from a lowered serum calcium level might be largely ascribable to the improvement of the alimentary balance of calcium. Also, the decrease in serum inorganic phosphate value might have been brought about by the suppression of phosphorus absorption by supplementary calcium lactate administraion, by phosphorus deposition in bones, and by suppression of bone resorption by PTH. It was found that a calcium concentration of 3.5 mEq / L approx, in the dialysate was adequate for periodic hemodialysis. The data indicated the effectiveness of the administration of 1α-OH-D3 with calcium supplementation for the prevention and treatment of renal osteodystrophy in the maintenance of hemodialized patients.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.44.3-4.89
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 44, 号 3-4, p. 89-101, 発行日 1982-03
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4434/4434.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17400
識別子タイプ HDL
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