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Delayed Recovery of Mitochondrial Function in Rat Liver after Releasing Biliary Obstruction
https://doi.org/10.18999/nagjms.45.3-4.97
https://doi.org/10.18999/nagjms.45.3-4.97beb40cb6-3178-41b6-9665-bd062b45b53c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
v45n34p97_105.pdf (1.2 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-01-28 | |||||
| タイトル | ||||||
| タイトル | Delayed Recovery of Mitochondrial Function in Rat Liver after Releasing Biliary Obstruction | |||||
| 言語 | en | |||||
| 著者 |
MIYATA, KANJI
× MIYATA, KANJI |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Liver mitochondria | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Respiratory function | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Ultrastructure | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | obstructive jaundice | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Bile drainage | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In order to know the influence of obstructive jaundice on the function of the liver and also to clarify the underlying factors involved in the recovery process after releasing biliary obstruction. the author examined the following parameters: The respiratory function of the liver mitochondria, the activities of hepatic enzymes in serum and the ultrastructure of the liver. Male Donryu rats were used for this investigation, in which the bile ducts of the rats were obstructed and, after a certain duration, were relased to allow for external bile drainage. The parameters mentioned above deteriorated due to obstructive jaundice, but recovered to some extent upon the release of the biliary obstruction. The recovery process depended on the length of the obstruction period. The longer the obstruction period persisted, the longer was the time required for recovery. Accordingly, it is desirable to perform biliary decompression as soon as possible, at least within a period of two weeks. Furthermore, after the release of obstructive jaundice, there existed a certain period of insufficient recovery of the mitochondrial function even when the biochemical data were completely normalized. This time lag of the recovery between mitochondrial function and biochemical data might reflect a reduced reserve function of the liver. Better understanding of the recovery process of the damaged liver is very important when considering major surgery after releasing obstructive jaundice. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.45.3-4.97 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4534/4534.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 45, 号 3-4, p. 97-105, 発行日 1983-06 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/17414 | |||||
| 識別子タイプ | HDL | |||||
