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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 45(3-4)

Delayed Recovery of Mitochondrial Function in Rat Liver after Releasing Biliary Obstruction

https://doi.org/10.18999/nagjms.45.3-4.97
https://doi.org/10.18999/nagjms.45.3-4.97
beb40cb6-3178-41b6-9665-bd062b45b53c
名前 / ファイル ライセンス アクション
v45n34p97_105.pdf v45n34p97_105.pdf (1.2 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-01-28
タイトル
タイトル Delayed Recovery of Mitochondrial Function in Rat Liver after Releasing Biliary Obstruction
著者 MIYATA, KANJI

× MIYATA, KANJI

WEKO 46934

MIYATA, KANJI

Search repository
キーワード
主題Scheme Other
主題 Liver mitochondria
キーワード
主題Scheme Other
主題 Respiratory function
キーワード
主題Scheme Other
主題 Ultrastructure
キーワード
主題Scheme Other
主題 obstructive jaundice
キーワード
主題Scheme Other
主題 Bile drainage
抄録
内容記述 In order to know the influence of obstructive jaundice on the function of the liver and also to clarify the underlying factors involved in the recovery process after releasing biliary obstruction. the author examined the following parameters: The respiratory function of the liver mitochondria, the activities of hepatic enzymes in serum and the ultrastructure of the liver. Male Donryu rats were used for this investigation, in which the bile ducts of the rats were obstructed and, after a certain duration, were relased to allow for external bile drainage. The parameters mentioned above deteriorated due to obstructive jaundice, but recovered to some extent upon the release of the biliary obstruction. The recovery process depended on the length of the obstruction period. The longer the obstruction period persisted, the longer was the time required for recovery. Accordingly, it is desirable to perform biliary decompression as soon as possible, at least within a period of two weeks. Furthermore, after the release of obstructive jaundice, there existed a certain period of insufficient recovery of the mitochondrial function even when the biochemical data were completely normalized. This time lag of the recovery between mitochondrial function and biochemical data might reflect a reduced reserve function of the liver. Better understanding of the recovery process of the damaged liver is very important when considering major surgery after releasing obstructive jaundice.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.45.3-4.97
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 45, 号 3-4, p. 97-105, 発行日 1983-06
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4534/4534.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17414
識別子タイプ HDL
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