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The Effect of Cimetidine and Hypoxia on the Gastric Macromolecular Glycoprotein in Rat
https://doi.org/10.18999/nagjms.48.1-4.27
https://doi.org/10.18999/nagjms.48.1-4.2755b39cc6-3e1d-4623-868b-82275cf158a8
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
v48n14p27_32.pdf (412.6 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-02-13 | |||||
| タイトル | ||||||
| タイトル | The Effect of Cimetidine and Hypoxia on the Gastric Macromolecular Glycoprotein in Rat | |||||
| 言語 | en | |||||
| 著者 |
NAKAZAWA, SABURO
× NAKAZAWA, SABURO× SEGAWA, KOSE× TSUKAMOTO, YOSIHISA× OKADA, MASANORI× KOBAYASHI, EIJI× YAMAGUCHI, HATSUHIRO× GOTO, HIDEMI× KURITA, YASUMITSU× FUKUI, AKIRA |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Glycoprotein Rat | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Hypoxia | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Gastric mucosal lesion | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Cimetidine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In an experimental study in rats, cimetidine, a potent gastric-acid inhibitor (50 mg/kg, .p.o.) reduced the macromolecular glycoprotein level of glandular stomach. The administration of cimetidine at a dose of 50 mg/kg, which inhibited the gastric lesions induced by hypoxia (13% O2 for 6 hours), reduced the glandular stomach level of high molecular glycoproteins in animals receiving a low oxygen load as well as in those receiving no load. It was assumed that the reduction of macromolecular glycoprotein accelerated the gastric lesion induced by hypoxia load in rats and that cimetidine inhibited the lesions through a process other than that of recovering the glycoprotein level in the glandular stomach. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.48.1-4.27 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4814/4814.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 48, 号 1-4, p. 27-32, 発行日 1986-03 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/17489 | |||||
| 識別子タイプ | HDL | |||||
