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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 48(1-4)

The Effect of Cimetidine and Hypoxia on the Gastric Macromolecular Glycoprotein in Rat

https://doi.org/10.18999/nagjms.48.1-4.27
https://doi.org/10.18999/nagjms.48.1-4.27
55b39cc6-3e1d-4623-868b-82275cf158a8
名前 / ファイル ライセンス アクション
v48n14p27_32.pdf v48n14p27_32.pdf (412.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-02-13
タイトル
タイトル The Effect of Cimetidine and Hypoxia on the Gastric Macromolecular Glycoprotein in Rat
著者 NAKAZAWA, SABURO

× NAKAZAWA, SABURO

WEKO 47138

NAKAZAWA, SABURO

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SEGAWA, KOSE

× SEGAWA, KOSE

WEKO 47139

SEGAWA, KOSE

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TSUKAMOTO, YOSIHISA

× TSUKAMOTO, YOSIHISA

WEKO 47140

TSUKAMOTO, YOSIHISA

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OKADA, MASANORI

× OKADA, MASANORI

WEKO 47141

OKADA, MASANORI

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KOBAYASHI, EIJI

× KOBAYASHI, EIJI

WEKO 47142

KOBAYASHI, EIJI

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YAMAGUCHI, HATSUHIRO

× YAMAGUCHI, HATSUHIRO

WEKO 47143

YAMAGUCHI, HATSUHIRO

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GOTO, HIDEMI

× GOTO, HIDEMI

WEKO 47144

GOTO, HIDEMI

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KURITA, YASUMITSU

× KURITA, YASUMITSU

WEKO 47145

KURITA, YASUMITSU

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FUKUI, AKIRA

× FUKUI, AKIRA

WEKO 47146

FUKUI, AKIRA

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キーワード
主題Scheme Other
主題 Glycoprotein Rat
キーワード
主題Scheme Other
主題 Hypoxia
キーワード
主題Scheme Other
主題 Gastric mucosal lesion
キーワード
主題Scheme Other
主題 Cimetidine
抄録
内容記述 In an experimental study in rats, cimetidine, a potent gastric-acid inhibitor (50 mg/kg, .p.o.) reduced the macromolecular glycoprotein level of glandular stomach. The administration of cimetidine at a dose of 50 mg/kg, which inhibited the gastric lesions induced by hypoxia (13% O2 for 6 hours), reduced the glandular stomach level of high molecular glycoproteins in animals receiving a low oxygen load as well as in those receiving no load. It was assumed that the reduction of macromolecular glycoprotein accelerated the gastric lesion induced by hypoxia load in rats and that cimetidine inhibited the lesions through a process other than that of recovering the glycoprotein level in the glandular stomach.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.48.1-4.27
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 48, 号 1-4, p. 27-32, 発行日 1986-03
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4814/4814.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17489
識別子タイプ HDL
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