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Role of Sympathoadrenal and Renin-Angiotensin System in Hemodynamic State after Coronary Artery Bypass Grafting
https://doi.org/10.18999/nagjms.49.1-4.1
https://doi.org/10.18999/nagjms.49.1-4.1baf4b8ef-f103-4d69-8a93-12d85d052e2e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
v49n14p1_15.pdf (954.5 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-02-13 | |||||
| タイトル | ||||||
| タイトル | Role of Sympathoadrenal and Renin-Angiotensin System in Hemodynamic State after Coronary Artery Bypass Grafting | |||||
| 言語 | en | |||||
| 著者 |
HAYASE, SHOOHEI
× HAYASE, SHOOHEI× SHIMIZU, TAKESHI× NAKAJIMA, MASAMICHI |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Coronary artery bypass grafting | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Renin-angiotensin system | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Sympathoadrenal system | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Hypertension | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Perioperative myocardial infarction | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To evaluate the role of the sympathoadrenal and renin-angiotensin systems in postoperative hemodynamic state, plasma concentrations of catecholamines, renin activity, angiotensin, and aldosterone as well as hemodynamics were studied following coronary artery bypass grafting in 55 patients. The patients were divided into four groups: 1) uneventful, 2) hypertension (HT), 3) hypotension for which cateeholamines were administered (CAT), and 4) perioperative myocardial infarction (POMI). The mean cardiac index in the HT group was higher than that in the Uneventful group and some patients in the HT group showed high adrenaline level. A group of patients who had a hypertensive episode and then sustained low cardiac output state (HT-to-LOS group) showed marked elevation of systemic vascular resistance index and noradrenaline level. These findings suggest that the hypertensive episodes in the HT-to-LOS group may be primarily caused by the activation of the sympathetic nerve system and that those of some patients in the HT group may be caused by marked adrenal medullary secretion. Five patients (56%) in the HT group showed plasma renin activity of more than 5.0 ng/ml/hr, and three patients (33%) showed angiotensin II of more than 100 pg/ml. Thus, postoperative hypertension seems to be multifactorial in nature. The POMI group represented significant elevation of plasma adrenaline concentration and significantly low sensitivity to catecholamines of the ventricle accompanied with impaired left ventricular performance. Although the mean aldosterone level in the CAT group was significantly higher than that in the Uneventful group, only a few patients of the CAT group demonstrated marked elevation of aldosterone concentration which might cause a vicious circle to develop. Clinical significance of modest increase of aldosterone concentration in other patients in the CAT group is questionable. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.49.1-4.1 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4914/4914.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 49, 号 1-4, p. 1-15, 発行日 1987-03 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/17493 | |||||
| 識別子タイプ | HDL | |||||
