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The Effect of Hypophysectomy on Proluminal Movement of 3H-Androgens Across the Epididymal Epithelium in the Rat
https://doi.org/10.18999/nagjms.54.1-4.67
https://doi.org/10.18999/nagjms.54.1-4.67437f4b19-a0fc-4379-ab25-902e11eac9cd
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
v54n14p67_76.pdf (582.8 kB)
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| アイテムタイプ | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2013-02-14 | |||||
| タイトル | ||||||
| タイトル | The Effect of Hypophysectomy on Proluminal Movement of 3H-Androgens Across the Epididymal Epithelium in the Rat | |||||
| 言語 | en | |||||
| 著者 |
YAMAMOTO, MASANORI
× YAMAMOTO, MASANORI× TSUJI, YOSHIKAZU× NAGAI, TATSUYA× MIYAKE, KOJI |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Testosterone | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Epididymis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Hypophysectomy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Micropuncture | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Microperifusion | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The effect of hypophysectomy on transepithelial movement of 3H-androgen in the rat epididymis was examined by using in vivo microperifusion of 3H-testosterone followed by in vivo micropuncture to obtain peritubular and intraluminal fluids. Experiments were performed on aminals without hypophysectomy or on aminals 5-6 days after hypophysectomy and 9-10 days after hypophysectomy. Tubules were perifused with Minimum Essential Medium containing 3H-testosterone. 14C-polyethyleneglycol was included in the perifusion fluid as a marker for contamination of the intraluminal fluid by peritubular fluid. Radioactivity of isotopes in the interstitial and intraluminal fluid was determined at 1 and 2 hours after perifusion and the percentage of peritubular isotopes appearing in the intraluminal fluid was determined. A sperm concentration microassay was performed on micropuncture samples from the epididymal tubules to assess testicular contribution to the lumen content. Proluminal movement of 3H-androgen and intratubular sperm concentrations in the caput epididymal tubules of rats 9-10 days after hypophysectomy were significantly decreased. Proluminal movement of 3H-androgen and intratubular sperm concentrations in the cauda epididymal tubules of rats 9-10 days after hypophysectomy were significantly increased. These results suggest that proluminal androgen movement is controlled by the presence of some testicular product in the epididymal lumen. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.54.1-4.67 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5414/5414.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 54, 号 1-4, p. 67-76, 発行日 1992-03 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/17523 | |||||
| 識別子タイプ | HDL | |||||
