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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 54(1-4)

The Effect of Hypophysectomy on Proluminal Movement of 3H-Androgens Across the Epididymal Epithelium in the Rat

https://doi.org/10.18999/nagjms.54.1-4.67
437f4b19-a0fc-4379-ab25-902e11eac9cd
名前 / ファイル ライセンス アクション
v54n14p67_76.pdf v54n14p67_76.pdf (582.8 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-02-14
タイトル
タイトル The Effect of Hypophysectomy on Proluminal Movement of 3H-Androgens Across the Epididymal Epithelium in the Rat
著者 YAMAMOTO, MASANORI

× YAMAMOTO, MASANORI

WEKO 47305

YAMAMOTO, MASANORI

Search repository
TSUJI, YOSHIKAZU

× TSUJI, YOSHIKAZU

WEKO 47306

TSUJI, YOSHIKAZU

Search repository
NAGAI, TATSUYA

× NAGAI, TATSUYA

WEKO 47307

NAGAI, TATSUYA

Search repository
MIYAKE, KOJI

× MIYAKE, KOJI

WEKO 47308

MIYAKE, KOJI

Search repository
キーワード
主題Scheme Other
主題 Testosterone
キーワード
主題Scheme Other
主題 Epididymis
キーワード
主題Scheme Other
主題 Hypophysectomy
キーワード
主題Scheme Other
主題 Micropuncture
キーワード
主題Scheme Other
主題 Microperifusion
抄録
内容記述 The effect of hypophysectomy on transepithelial movement of 3H-androgen in the rat epididymis was examined by using in vivo microperifusion of 3H-testosterone followed by in vivo micropuncture to obtain peritubular and intraluminal fluids. Experiments were performed on aminals without hypophysectomy or on aminals 5-6 days after hypophysectomy and 9-10 days after hypophysectomy. Tubules were perifused with Minimum Essential Medium containing 3H-testosterone. 14C-polyethyleneglycol was included in the perifusion fluid as a marker for contamination of the intraluminal fluid by peritubular fluid. Radioactivity of isotopes in the interstitial and intraluminal fluid was determined at 1 and 2 hours after perifusion and the percentage of peritubular isotopes appearing in the intraluminal fluid was determined. A sperm concentration microassay was performed on micropuncture samples from the epididymal tubules to assess testicular contribution to the lumen content. Proluminal movement of 3H-androgen and intratubular sperm concentrations in the caput epididymal tubules of rats 9-10 days after hypophysectomy were significantly decreased. Proluminal movement of 3H-androgen and intratubular sperm concentrations in the cauda epididymal tubules of rats 9-10 days after hypophysectomy were significantly increased. These results suggest that proluminal androgen movement is controlled by the presence of some testicular product in the epididymal lumen.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.54.1-4.67
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 54, 号 1-4, p. 67-76, 発行日 1992-03
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5414/5414.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17523
識別子タイプ HDL
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