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Studies on Heterogeneity of Fibrinolytic Activity in Artificially Induced Intravascular Clots
https://doi.org/10.18999/nagjms.30.1.37
https://doi.org/10.18999/nagjms.30.1.37394530ce-6443-446c-9f25-12565a61395e
名前 / ファイル | ライセンス | アクション |
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v30n1p37_57.pdf (2.7 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-09-25 | |||||
タイトル | ||||||
タイトル | Studies on Heterogeneity of Fibrinolytic Activity in Artificially Induced Intravascular Clots | |||||
言語 | en | |||||
著者 |
BAN, ICHIRO
× BAN, ICHIRO |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
抄録 | ||||||
内容記述 | This study was designed to investigate the effectiveness of enhancing local fibrinolytic actvity in intravascular clots preventing side reactions resulting from fibrinolytic activation in the circulating blood. For this purpose, the following procedures were performed. Artificial intravenous clots were induced in femoral and external jugular veins of dogs by three different methods. To dogs at various time intervals after clot formation, EACA or trans-AMCHA was intravenously injected following with simultaneous human serum, and then various units of streptokinase or urokinase were intravenously administrated. Fibrinolytic activity of these clots after treatment was assayed according to the fibrin plate method, at the same time fibrinolytic activity of a thrombosed vein was assayed. The results of these experiments were as follows: 1) Artificially induced intravenous clots showed no fibrinolytic activity except thrombin-induced clots. 2) Activator activity of one hour to six day old clots treated with EACA or trans-AMCHA was significantly enhanced by the simultaneous injection of streptokinase or urokinase. 3) Activator activity of intima of a thrombosed vein was also enhanced with streptokinase or urokinase. 4) The administration of EACA or trans-AMCHA did not sacrifice the fibrinolytic activation in an intravenous clot with streptokinase or urokinase. 5) A fibrinolytic mechanism in an intravascular clot showed different characteristics from that of the circulation. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.30.1.37 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/301/301.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 30, 号 1, p. 37-57, 発行日 1967-06 |
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著者版フラグ | ||||||
値 | publisher |