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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 30(1)

Effects of Ouabain and Catecholamines on the Refractory Periods and Contractions of Isolated Atria

https://doi.org/10.18999/nagjms.30.1.121
https://doi.org/10.18999/nagjms.30.1.121
582664dd-bbc2-4d35-9dea-6f14a4dbaba4
名前 / ファイル ライセンス アクション
v30n1p121_128.pdf v30n1p121_128.pdf (899.2 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-09-25
タイトル
タイトル Effects of Ouabain and Catecholamines on the Refractory Periods and Contractions of Isolated Atria
著者 MAEDA, KIYOSHI

× MAEDA, KIYOSHI

WEKO 93930

MAEDA, KIYOSHI

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ITO, KEIZO

× ITO, KEIZO

WEKO 93931

ITO, KEIZO

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SEKIYA, ATSUSHI

× SEKIYA, ATSUSHI

WEKO 93932

SEKIYA, ATSUSHI

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KANDA, ZENGO

× KANDA, ZENGO

WEKO 93933

KANDA, ZENGO

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抄録
内容記述 Effects of ouabain and catecholamines_ and their modifications_ by propranolol were investigated on the functional refractory period (FRP), contractile force and heart rate in isolated atria of guinea-pigs and rats. Catecholamines produced a transient decrease in the FRP of guinea-pig atria, while ouabain caused a continual increase after a latent period of 5 to 10 minutes. The FRP in rat atria was_ increased by either ouabain or catecholamines. Pretreament with propranolol, which by itself produced a moderate increase in the FRP, completely blocked the effects of catecholamines, but did not prevent those of ouabain in both atria. It seems from these data on the FRP changes_ that no evidence was_ obtained for a ouabain-catecholamine relationship. However, from the observation on the spontaneously beating atria that the toxic effects of ouabain on contractility and rhythmicity were markedly reduced by propranolol it would be suggested that catecholamines might be related to the action of ouabain in its toxic stage.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.30.1.121
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/301/301.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 30, 号 1, p. 121-128, 発行日 1967-06
著者版フラグ
値 publisher
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