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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Tissue characterization by magnetization transfer ratio : Evaluate of the MTRs in breast tunors, globus pallidus and nasopharyngeal tumors

http://hdl.handle.net/2237/19565
7fb16b95-d639-45db-b027-315f9a81342a
名前 / ファイル ライセンス アクション
49_TissueCharacterizationByMTR.pdf 49_TissueCharacterizationByMTR.pdf (571.5 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-03-11
タイトル
タイトル Tissue characterization by magnetization transfer ratio : Evaluate of the MTRs in breast tunors, globus pallidus and nasopharyngeal tumors
著者 Matsushima, Shigeru

× Matsushima, Shigeru

WEKO 51370

Matsushima, Shigeru

Search repository
Sasaki, Fumio

× Sasaki, Fumio

WEKO 51371

Sasaki, Fumio

Search repository
Uchiyama, Yukio

× Uchiyama, Yukio

WEKO 51372

Uchiyama, Yukio

Search repository
Fuwa, Nobukazu

× Fuwa, Nobukazu

WEKO 51373

Fuwa, Nobukazu

Search repository
Andoh, Manabu

× Andoh, Manabu

WEKO 51374

Andoh, Manabu

Search repository
Maeda, Hisatochi

× Maeda, Hisatochi

WEKO 51375

Maeda, Hisatochi

Search repository
Kinosada, Yasutomi

× Kinosada, Yasutomi

WEKO 51376

Kinosada, Yasutomi

Search repository
キーワード
主題Scheme Other
主題 magnetization transfer ratio
キーワード
主題Scheme Other
主題 MRI
キーワード
主題Scheme Other
主題 tissue characterization
抄録
内容記述 Magnetization transfer ratios (MTRs) of tissues with different characteristics were investigated. Cross-relaxation rates of solutions with different protein concentrations were studied. We evaluated the MTRs of female breast tumors, the globus pallidus, and nasopharyngeal tumors, and assessed the usefulness of MTRs in determining tissue characteristics. In phantom studies, we measured MTRs using gelatin and MnCl2 solution with various concentrations of gelatin and MnCl2. MTRs were measured using pairs of images obtained by conventional SPGR sequence and MT-prepared SPGR sequence. MTRs, defined as the percentage of signal loss between unsaturated and saturated images, were calculated using the equation (Mo - Ms) / Mo, where Mo is the measured signal intensity on the conventional SPGR images, and Ms is the measured signal intensity on the MT-prepared SPGR images. We investigated relationships between pathological findings and MTRs of breast tumors, between liver function and MTRs of globus pallidus, and between the DNA index and MTRs of nasopharyngeal tumors. MTRs increased with increased gelatin concentration, but decreased as the MnCl2 concentration increased. MTRs of breast carcinoma were higher than those of benign tumors. MTRs of globus pallidus showed a correlation with liver function (ChE:r = 0.79, PT: r = 0.75, ICGR15: r = -0.98). MTRs of aneuploid nasopharyngeal tumors had high MTRs. MTR is a good indicator of protein concentration and could be a new and useful parameter for tissue characterization.
内容記述タイプ Abstract
出版者
出版者 日本医学放射線物理学会
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0918-8010
書誌情報 放射線医学物理 = Japanese journal of medical physics

巻 17, 号 1, p. 1-8, 発行日 1997-03
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/19565
識別子タイプ HDL
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