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Iron Metabolism and Autophagy: A Poorly Explored Relationship that has Important Consequences for Health and Disease
https://doi.org/10.18999/nagjms.77.1-2.1
https://doi.org/10.18999/nagjms.77.1-2.1c1a85dbd-a1f4-42a5-9e2c-ab6a542129c5
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
01_Richardson.pdf (268.8 kB)
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| アイテムタイプ | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-02-25 | |||||
| タイトル | ||||||
| タイトル | Iron Metabolism and Autophagy: A Poorly Explored Relationship that has Important Consequences for Health and Disease | |||||
| 言語 | en | |||||
| 著者 |
KRISHAN, SUKRITI
× KRISHAN, SUKRITI× JANSSON, PATRIC J.× GUTIERREZ, ELAINE× LANE, DARIUS J.R.× RICHARDSON, DES× SAHNI, SUMIT |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Autophagy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Iron metabolism | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Chelators | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Autophagy is an important cell survival pathway which is up-regulated under stress conditions.1) It is a well regulated catabolic process and enables the cell to recycle its constituents and organelles for re-use.1) Autophagy has been implicated to play an important role in a variety of disorders such as cancer and protein aggregatory neurodegenerative diseases e.g., Alzheimer’s disease, Parkinson’s disease and Huntington’s disease.2) Iron is a critical metal required for normal cellular functioning.3) A very tightly regulated balance of iron levels is required for the normal physiological functioning of the cell.3) Both an excess and deficiency of iron can lead to cellular stress, and thereby, alters the autophagic status within the cell. Thus, it is important to completely understand how iron can affect the autophagic pathway and its potential implications under physiological as well as pathological conditions. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.77.1-2.1 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7712.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 77, 号 1-2, p. 1-6, 発行日 2015-02 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/21253 | |||||
| 識別子タイプ | HDL | |||||
