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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 77(1-2)

Iron Metabolism and Autophagy: A Poorly Explored Relationship that has Important Consequences for Health and Disease

https://doi.org/10.18999/nagjms.77.1-2.1
https://doi.org/10.18999/nagjms.77.1-2.1
c1a85dbd-a1f4-42a5-9e2c-ab6a542129c5
名前 / ファイル ライセンス アクション
01_Richardson.pdf 01_Richardson.pdf (268.8 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-02-25
タイトル
タイトル Iron Metabolism and Autophagy: A Poorly Explored Relationship that has Important Consequences for Health and Disease
著者 KRISHAN, SUKRITI

× KRISHAN, SUKRITI

WEKO 55961

KRISHAN, SUKRITI

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JANSSON, PATRIC J.

× JANSSON, PATRIC J.

WEKO 55962

JANSSON, PATRIC J.

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GUTIERREZ, ELAINE

× GUTIERREZ, ELAINE

WEKO 55963

GUTIERREZ, ELAINE

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LANE, DARIUS J.R.

× LANE, DARIUS J.R.

WEKO 55964

LANE, DARIUS J.R.

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RICHARDSON, DES

× RICHARDSON, DES

WEKO 55965

RICHARDSON, DES

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SAHNI, SUMIT

× SAHNI, SUMIT

WEKO 55966

SAHNI, SUMIT

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キーワード
主題Scheme Other
主題 Autophagy
キーワード
主題Scheme Other
主題 Iron metabolism
キーワード
主題Scheme Other
主題 Chelators
抄録
内容記述 Autophagy is an important cell survival pathway which is up-regulated under stress conditions.1) It is a well regulated catabolic process and enables the cell to recycle its constituents and organelles for re-use.1) Autophagy has been implicated to play an important role in a variety of disorders such as cancer and protein aggregatory neurodegenerative diseases e.g., Alzheimer’s disease, Parkinson’s disease and Huntington’s disease.2) Iron is a critical metal required for normal cellular functioning.3) A very tightly regulated balance of iron levels is required for the normal physiological functioning of the cell.3) Both an excess and deficiency of iron can lead to cellular stress, and thereby, alters the autophagic status within the cell. Thus, it is important to completely understand how iron can affect the autophagic pathway and its potential implications under physiological as well as pathological conditions.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.77.1-2.1
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 77, 号 1-2, p. 1-6, 発行日 2015-02
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7712.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/21253
識別子タイプ HDL
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