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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 77(1-2)

Tuberculosis and Rifanpicin Resistance among Migrants in Kyrgyzstan: Detection by a New Diagnostic Test

https://doi.org/10.18999/nagjms.77.1-2.41
https://doi.org/10.18999/nagjms.77.1-2.41
766f09d4-ad4d-43e4-9612-dc2a96e5f6b7
名前 / ファイル ライセンス アクション
11_Barmankulova.pdf 11_Barmankulova.pdf (150.3 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-02-26
タイトル
タイトル Tuberculosis and Rifanpicin Resistance among Migrants in Kyrgyzstan: Detection by a New Diagnostic Test
著者 BARMANKULOVA, AIGUL

× BARMANKULOVA, AIGUL

WEKO 55976

BARMANKULOVA, AIGUL

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HIGUCHI, MICHIYO

× HIGUCHI, MICHIYO

WEKO 55977

HIGUCHI, MICHIYO

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MOHAMMAD, ABUL BASHAR SARKER

× MOHAMMAD, ABUL BASHAR SARKER

WEKO 55978

MOHAMMAD, ABUL BASHAR SARKER

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MD., ABDUL ALIM

× MD., ABDUL ALIM

WEKO 55979

MD., ABDUL ALIM

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HAMAJIMA, NOBUYUKI

× HAMAJIMA, NOBUYUKI

WEKO 55980

HAMAJIMA, NOBUYUKI

Search repository
キーワード
主題Scheme Other
主題 Tuberculosis
キーワード
主題Scheme Other
主題 MDR-TB
キーワード
主題Scheme Other
主題 Migrants
キーワード
主題Scheme Other
主題 Xpert MTB/RIF
キーワード
主題Scheme Other
主題 Kyrgyzstan
抄録
内容記述 This cross-sectional study aimed to describe suspected tuberculosis (TB) cases among migrants in Kyrgyzstan and to estimate the accuracy of Xpert MTB/RIF, which has been operated in Kyrgyzstan since 2012. Characteristics of 3,714 suspected cases among migrants were analysed. In addition, by using data of 300 cases with culture results, sensitivity and specificity of Xpert MTB/RIF, both for detection of TB and rifampicin susceptibility, were assessed. Among 3,714 suspected cases, 56.1% were male, and the median age was 35 years old. Of the suspected cases, 17.2% were previously-treated. In total, 809 (21.8%) were smear-positive; 36.8% among previously-treated cases and 18.7% among new cases. Among 300 selected participants, 235 (78.3%) were culture-positive. Of those who were confirmed as TB positive, recurrent cases showed a higher proportion of rifampicin resistance than new cases (59.3% vs 42.6%). For detection of TB, the sensitivity and specificity of XpertMTB/RIF (81.3% and 98.2%) were higher than those of microscopy (70.2% and 71.4%). Sensitivity and specificity for detection of rifampicin resistance were 96.8% and 91.8%, respectively. The rifampicin resistance rate in the study population was higher than the national average. Xpert MTB/RIF showed higher accuracy in detecting TB cases than microscopic diagnosis. Higher accuracy and earlier detection of drug susceptibility is especially important for those who have difficulty in accessing healthcare and those who are easily lost from tracking, including migrants.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.77.1-2.41
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 77, 号 1-2, p. 41-49, 発行日 2015-02
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7712.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/21257
識別子タイプ HDL
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