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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 77(1-2)

Left Ventricular Dyssynchrony in Patients with Moderate Coronary Stenosis and Border Line Fractional Flow Reserve

https://doi.org/10.18999/nagjms.77.1-2.155
https://doi.org/10.18999/nagjms.77.1-2.155
e0cb89f0-e520-4b89-9f64-d663d83d1980
名前 / ファイル ライセンス アクション
22_Shibata.pdf 22_Shibata.pdf (901.0 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-02-26
タイトル
タイトル Left Ventricular Dyssynchrony in Patients with Moderate Coronary Stenosis and Border Line Fractional Flow Reserve
著者 SHIBATA, YOHEI

× SHIBATA, YOHEI

WEKO 56030

SHIBATA, YOHEI

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SONE, TAKAHITO

× SONE, TAKAHITO

WEKO 56031

SONE, TAKAHITO

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TSUBOI, HIDEYUKI

× TSUBOI, HIDEYUKI

WEKO 56032

TSUBOI, HIDEYUKI

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ISOBE, SATOSHI

× ISOBE, SATOSHI

WEKO 56033

ISOBE, SATOSHI

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ISHII, HIDEKI

× ISHII, HIDEKI

WEKO 56034

ISHII, HIDEKI

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SUZUKI, SUSUMU

× SUZUKI, SUSUMU

WEKO 56035

SUZUKI, SUSUMU

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HAYASHI, MUTSUHARU

× HAYASHI, MUTSUHARU

WEKO 56036

HAYASHI, MUTSUHARU

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MUROHARA, TOYOAKI

× MUROHARA, TOYOAKI

WEKO 56037

MUROHARA, TOYOAKI

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キーワード
主題Scheme Other
主題 left ventricular dyssynchrony
キーワード
主題Scheme Other
主題 fractional flow reserve
キーワード
主題Scheme Other
主題 stress electrocardiographically-gated myocardial perfusion single-photon emission computed tomography
抄録
内容記述 The cutoff values of fractional flow reserve (FFR) to detect physiological myocardial ischemia are still controversial. Some studies have reported that left ventricular (LV) dyssynchrony occurs in patients with coronary artery disease (CAD). The purpose of this study was to investigate LV dyssynchrony in patients with moderate coronary stenosis and borderline FFR, using stress electrocardiographically-gated myocardial perfusion single-photon emission computed tomography (SPECT). The study population comprised 10 patients with moderate (50–75% diameter) stenosis and an FFR in the range 0.75–0.90, who were compared to 10 control subjects. All underwent stress myocardial 99mTc-sestamibi (MIBI) or tetrofosmin SPECT imaging. The regional time to end systole (TES), time to peak ejection (TPE), and time to peak filling (TPF) were obtained as indexes of perfusion and function, using gated SPECT (pFAST) in combination with Cardio Gated SPECT Regional Assessment for LV Function (cardioGRAF). The dyssynchrony index (DI) was also calculated. The DI of post-stress TES was significantly greater than that of rest in patients with moderate CAD (4.8 ± 2.8 vs. 2.7 ± 1.5, P = 0.01), but there were no significant differences in the control subjects (3.0 ± 1.7 vs. 2.9 ± 1.9, P = 0.99). There were no significant differences in TPE and TPF between the groups. In conclusion, LV dyssynchrony may occur after stress in patients with coronary stenosis and borderline FFR, even without a significant reduction in perfusion.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.77.1-2.155
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 77, 号 1-2, p. 155-166, 発行日 2015-02
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7712.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/21268
識別子タイプ HDL
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