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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 83(2)

Tooth brushing, tooth loss, and risk of upper aerodigestive tract cancer: a cohort study of Japanese dentisits

https://doi.org/10.18999/nagjms.83.2.331
https://doi.org/10.18999/nagjms.83.2.331
3b35d33c-cd38-4513-b3b8-1ddf401b1ea9
名前 / ファイル ライセンス アクション
12_Tsukamoto.pdf 12_Tsukamoto.pdf (227 KB)
Item type itemtype_ver1(1)
公開日 2021-06-25
タイトル
タイトル Tooth brushing, tooth loss, and risk of upper aerodigestive tract cancer: a cohort study of Japanese dentisits
言語 en
著者 Tsukamoto, Mineko

× Tsukamoto, Mineko

en Tsukamoto, Mineko

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Naito, Mariko

× Naito, Mariko

en Naito, Mariko

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Wakai, Kenji

× Wakai, Kenji

en Wakai, Kenji

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Naito, Toru

× Naito, Toru

en Naito, Toru

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Kojima, Masaaki

× Kojima, Masaaki

en Kojima, Masaaki

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Umemura, Osami

× Umemura, Osami

en Umemura, Osami

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Yokota, Makoto

× Yokota, Makoto

en Yokota, Makoto

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Hanada, Nobuhiro

× Hanada, Nobuhiro

en Hanada, Nobuhiro

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Kawamura, Takashi

× Kawamura, Takashi

en Kawamura, Takashi

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
主題Scheme Other
主題 toothbrushing
キーワード
主題Scheme Other
主題 tooth loss
キーワード
主題Scheme Other
主題 oral health
キーワード
主題Scheme Other
主題 head and neck cancer
キーワード
主題Scheme Other
主題 cohort study
内容記述
内容記述 Previous studies have focused on the association between poor oral health and upper aerodigestive tract (UADT) cancer. However, whether toothbrushing and tooth loss are associated with UADT cancer risk is still unclear. Therefore, we investigated the association between toothbrushing or tooth loss and UADT cancer in the Longitudinal Evaluation of Multi-phasic, Odontological, and Nutritional Associations in Dentists (LEMONADE) cohort study. From 2001 to 2006, we recruited 20,445 dentists (mean age ± standard deviation, 51.8 ± 12.0 years; 1,607 women [7.9%]) and followed for incidence or mortality of UADT cancer through March 2014. Information on lifestyle and oral health was collected by the baseline questionnaire. The Cox proportional hazards model was used to estimate hazard ratios (HRs) for UADT cancer and corresponding 95% confidence intervals (CI) for brushing frequency and tooth loss with adjustment for covariates. During the mean follow-up of 9.5 years, we confirmed 62 incident or fatal cases of UADT cancer. Infrequent toothbrushing (< 2 times/day) was significantly associated with increased risk of UADT cancer (multivariate HR = 2.13, 95% CI: 1.04–4.37). On the contrary, tooth loss was not significantly correlated with UADT cancer risk; multivariate HR was 1.03 (95% CI: 0.41–2.61) for loss of 15–27 teeth and 1.37 (0.50–3.75) for that of 28 teeth compared to tooth loss of 0–14 teeth. In conclusion, Infrequent toothbrushing was significantly associated with the risk of UADT cancer.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).
This study was also supported by MEXT/JSPS KAKENHI (grant numbers 14770166, 16390189, 2059642, 2359788, and 26463161) of the Japanese Ministry of Education, Culture, Sports, Science and Technology.
言語 en
内容記述タイプ Other
出版者
言語 en
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.83.2.331
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/832.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 83, 号 2, p. 331-341, 発行日 2021-05
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