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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 83(4)

Efficacy and safety of cyclooxygenase 2 inhibitors for desmoid tumor management: a systematic review

https://doi.org/10.18999/nagjms.83.4.673
https://doi.org/10.18999/nagjms.83.4.673
f9cc4de1-ecf3-4656-b8fe-8f06505c6681
名前 / ファイル ライセンス アクション
03_Emori.pdf 03_Emori.pdf (468 KB)
Item type itemtype_ver1(1)
公開日 2021-12-03
タイトル
タイトル Efficacy and safety of cyclooxygenase 2 inhibitors for desmoid tumor management: a systematic review
言語 en
著者 Emori, Makoto

× Emori, Makoto

en Emori, Makoto

Search repository
Matsumoto, Yoshihiro

× Matsumoto, Yoshihiro

en Matsumoto, Yoshihiro

Search repository
Murahashi, Yasutaka

× Murahashi, Yasutaka

en Murahashi, Yasutaka

Search repository
Yoshida, Masahiro

× Yoshida, Masahiro

en Yoshida, Masahiro

Search repository
Nishida, Yoshihiro

× Nishida, Yoshihiro

en Nishida, Yoshihiro

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
言語 en
主題Scheme Other
主題 cyclooxygenase 2 inhibitors
キーワード
言語 en
主題Scheme Other
主題 desmoid
キーワード
言語 en
主題Scheme Other
主題 response rate
キーワード
言語 en
主題Scheme Other
主題 adverse effect
キーワード
言語 en
主題Scheme Other
主題 systematic review
内容記述
内容記述 The efficacy and safety of cyclooxygenase 2 (COX2) inhibitors for the treatment of desmoid-type fibromatosis (DF) are unclear. Therefore, we systematically reviewed related literature to assess the efficacy and safety of COX2 inhibitors for DF treatment. We searched pertinent literature between January 1999 and August 2017 to identify relevant studies using the keywords “Fibromatosis, aggressive” and “Cyclooxygenase inhibitors.” Thereafter, we screened and determined the quality of the studies using the Grading of Recommendations Assessment, Development, and Evaluation system and extracted the article data. The critical outcomes selected were the efficacy and adverse effects of COX2 inhibitors. Efficacy was evaluated in terms of clinical benefit when patients showed complete response, partial response, and stable disease. Thirty-one articles were identified from the database search, and one was identified through the reviewers’ manual search. Finally, we retrieved six studies, including three case reports, comprising 89 patients after the first and second screenings. Fifty-three patients were excluded because three studies were reported from the same institution; hence, in total, 36 patients were included. Clinical benefit was noted in 64% of the patients. Three adverse effects were identified from the records of the six extracted studies. The strategy of watchful waiting using COX2 inhibitors with few side effects is weakly recommended for DF, especially DF patients with pain.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).
言語 en
内容記述タイプ Other
出版者
言語 en
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.83.4.673
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/834.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 83, 号 4, p. 673-681, 発行日 2021-11
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