{"_buckets": {"deposit": "a6fd46db-d3a3-49ad-a3f9-9be86239e91c"}, "_deposit": {"created_by": 17, "id": "2001767", "owner": "17", "owners": [17], "owners_ext": {"displayname": "\u56f3\u66f8\u60c5\u5831\u4fc2", "username": "repository"}, "pid": {"revision_id": 0, "type": "depid", "value": "2001767"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:02001767"}, "author_link": [], "item_1615768549627": {"attribute_name": "\u51fa\u7248\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_1629683748249": {"attribute_name": "\u65e5\u4ed8", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2022-06-01", "subitem_date_issued_type": "Available"}]}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2021-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "372", "bibliographicPageStart": "361", "bibliographicVolumeNumber": "153", "bibliographic_titles": [{"bibliographic_title": "Journal of Neuro-Oncology", "bibliographic_titleLang": "en"}]}]}, "item_9_description_4": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "Purpose: The aim of this study was to assess the effect of the extent of resection (EOR) of tumors on survival in a series of patients with grade II and III gliomas (GII/III-gliomas) who underwent awake brain mapping. Methods: We retrospectively analyzed 126 patients with GII/III-gliomas in the dominant and non-dominant hemisphere who underwent awake brain surgery at the same institution between December 2012 and May 2020. Results: EOR cut-off values for improved progression-free survival (PFS) were determined by a receiver operator characteristic (ROC) analysis of 5-year PFS. The ROC for EOR showed a cut-off value of\u2009\u2265\u200985.3%. The median PFS rate of patients with GII/III-gliomas in the group with an EOR\u2009\u2265\u2009100%, including supratotal resection (n\u2009=\u200947; median survival [MS], not reached), was significantly higher than that in the group with an EOR\u2009\u003c\u200990% (n\u2009=\u200952; MS, 43.1 months; 95% CI 37.7\u201348.5 months; p\u2009=\u20090.03). In patients with diffuse astrocytomas and anaplastic astrocytomas, the group with EOR\u2009\u2265\u2009100%, including supratotal resection (n\u2009=\u200925; MS, not reached), demonstrated a significantly better PFS rate than did the group with an EOR\u2009\u003c\u2009100% (n\u2009=\u200945; MS, 35.8 months; 95% CI 19.9\u201351.6 months; p\u2009=\u20090.03). Supratotal or gross total resection was correlated with better PFS in IDH-mutant type of diffuse astrocytomas and anaplastic astrocytomas (n\u2009=\u200919; MS, not reached vs. n\u2009=\u200935; MS, 40.6 months; 95% CI 22.3\u201359.0 months; p\u2009=\u20090.02). By contrast, supratotal or gross total resection was not associated with longer PFS rates in patients with IDH-wild type of diffuse astrocytomas and anaplastic astrocytomas. Conclusions: The present study demonstrates a significant association between tumor EOR and survival in patients with GII/III gliomas. The EOR cut-off value for 5-year PFS was\u2009\u2265\u200985.3%. It is noteworthy that supratotal or gross total resection significantly correlated with better PFS in IDH-mutant type of WHO grade II and III astrocytic tumors. In light of our finding that EOR did not correlate with PFS in patients with aggressive IDH-wild type of diffuse astrocytomas and anaplastic astrocytomas, we suggest treatments that are more intensive will be needed for the control of these tumors.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Springer", "subitem_publisher_language": "en"}]}, "item_9_relation_43": {"attribute_name": "\u95a2\u9023\u60c5\u5831", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1007/s11060-021-03776-w", "subitem_relation_type_select": "DOI"}}]}, "item_9_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature\u2019s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s11060-021-03776-w", "subitem_rights_language": "en"}]}, "item_9_source_id_7": {"attribute_name": "\u53ce\u9332\u7269\u8b58\u5225\u5b50", "attribute_value_mlt": [{"subitem_source_identifier": "0167-594X", "subitem_source_identifier_type": "PISSN"}]}, "item_access_right": {"attribute_name": "\u30a2\u30af\u30bb\u30b9\u6a29", "attribute_value_mlt": [{"subitem_access_right": "embargoed access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_f1cf"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Motomura, Kazuya", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Chalise, Lushun", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Ohka, Fumiharu", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Aoki, Kosuke", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Tanahashi, Kuniaki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Hirano, Masaki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Nishikawa, Tomohide", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yamaguchi, Junya", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Shimizu, Hiroyuki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Wakabayashi, Toshihiko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Saito, Ryuta", "creatorNameLang": "en"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2022-06-01"}], "displaytype": "detail", "download_preview_message": "Download / Preview is available from 2022/5/31.", "file_order": 0, "filename": "JOURNAL_OF_NEURO-ONCOLOGY_153_2_2021_361-372.pdf", "filesize": [{"value": "347 KB"}], "format": "application/pdf", "future_date_message": "Download is available from 2022/5/31.", "is_thumbnail": false, "mimetype": "application/pdf", "size": 347000.0, "url": {"objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/2001767/files/JOURNAL_OF_NEURO-ONCOLOGY_153_2_2021_361-372.pdf"}, "version_id": "f46151f5-c4ca-47f7-ab5d-eb3e3b50f40b"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Impact of the extent of resection on the survival of patients with grade II and III gliomas using awake brain mapping", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Impact of the extent of resection on the survival of patients with grade II and III gliomas using awake brain mapping", "subitem_title_language": "en"}]}, "item_type_id": "40001", "owner": "17", "path": ["499/500/501"], "permalink_uri": "http://hdl.handle.net/2237/0002001767", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2021-12-22"}, "publish_date": "2021-12-22", "publish_status": "0", "recid": "2001767", "relation": {}, "relation_version_is_last": true, "title": ["Impact of the extent of resection on the survival of patients with grade II and III gliomas using awake brain mapping"], "weko_shared_id": -1}