| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2022-01-11 |
| タイトル |
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|
タイトル |
Evaluation of the blood–perilymph barrier in ears with endolymphatic hydrops |
|
言語 |
en |
| 著者 |
Yoshida, Tadao
Kobayashi, Masumi
Sugimoto, Satofumi
Teranishi, Masaaki
Naganawa, Shinji
Sone, Michihiko
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| アクセス権 |
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|
アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利 |
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|
権利情報 |
This is an Accepted Manuscript of an article published by Taylor & Francis Group in Acta Oto-Laryngologica on 04/08/2021, available online: http://www.tandfonline.com/10.1080/00016489.2021.1957500. |
|
言語 |
en |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
MRI |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
endolymphatic hydrops |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
signal intensity |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
Background: Otological diseases including Meniere’s disease (MD) involve endolymphatic hydrops (EH), which can be visualized by magnetic resonance imaging (MRI) with gadolinium contrast agents, but the temporal changes of contrast in the inner ear have not been evaluated. Objectives: We investigated the permeability of the blood–perilymph barrier (BPB) in ears with EH to evaluate the severity of the inner ear disturbances. Materials and methods: The study included 32 ears from 16 patients with EH or related diseases who underwent MRI. The permeability of the BPB was assessed by the signal–intensity ratio (SIR) at four-time points: before and at 10 min, 4 h, and 24 h after administration of gadolinium for assessing EH. Results: Cochlear EH was found in 25 of the 32 ears, and vestibular EH in 11. The rate of EH was significantly higher in symptomatic ears; however, the existence of EH was not related to SIR values. Nevertheless, SIR values in the basal turn were significantly higher 4 and 24 h after injection of gadolinium in patients aged ≥50 years. Conclusion and significance: Higher SIR values observed in older patients with EH indicate severe disturbances of the BPB in the cochlea, which may account for intractable inner ear disturbances in older patients. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Taylor & Francis |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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|
資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1080/00016489.2021.1957500 |
| 収録物識別子 |
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|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0001-6489 |
| 書誌情報 |
en : Acta Oto-Laryngologica
巻 141,
号 8,
p. 736-741,
発行日 2021-08-04
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| ファイル公開日 |
|
|
日付 |
2022-08-04 |
|
日付タイプ |
Available |
SOTO-2021-0322_Proof_hi.pdf (936 KB)
