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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 84(1)

The equilibrated blood sevoflurane concentrations show a rapid decrease after switching from ventilation for the human lung to cardiopulmonary bypass

https://doi.org/10.18999/nagjms.84.1.163
https://doi.org/10.18999/nagjms.84.1.163
1e759c0b-7bfe-442d-bdab-9a9ee9b11afa
名前 / ファイル ライセンス アクション
17_Tamura.pdf 17_Tamura.pdf (785 KB)
Item type itemtype_ver1(1)
公開日 2022-02-28
タイトル
タイトル The equilibrated blood sevoflurane concentrations show a rapid decrease after switching from ventilation for the human lung to cardiopulmonary bypass
言語 en
著者 Tamura, Takahiro

× Tamura, Takahiro

en Tamura, Takahiro

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Mori, Atsushi

× Mori, Atsushi

en Mori, Atsushi

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Ishii, Akira

× Ishii, Akira

en Ishii, Akira

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Nishiwaki, Kimitoshi

× Nishiwaki, Kimitoshi

en Nishiwaki, Kimitoshi

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
言語 en
主題Scheme Other
主題 cardiopulmonary bypass
キーワード
言語 en
主題Scheme Other
主題 sevoflurane
キーワード
言語 en
主題Scheme Other
主題 blood concentration
キーワード
言語 en
主題Scheme Other
主題 oxygenator
キーワード
言語 en
主題Scheme Other
主題 human lung ventilation
内容記述
内容記述 Volatile anesthetics (VAs) protect myocardial cells during cardiovascular surgeries, including cardiopulmonary bypass (CPB). In CPB, blood is gradually transferred from the body to a CPB unit until the target cardiac index is achieved, following which human lung (HL) ventilation is stopped. This pilot study aimed to evaluate changes in the blood sevoflurane concentrations 5 min after the start of CPB when its delivery to the oxygenator began after HL ventilation with sevoflurane was completed. Six patients were recruited and participated in this study. For each patient, the equilibrated blood sample, collected 20 min after starting the delivery of 1.7% sevoflurane (HL group), and another blood sample, collected 5 min after starting the CPB, were analyzed using gas chromatography equipped with a flame ionization detector. The mean (± standard deviation) sevoflurane concentrations in the HL and 5 min after starting CPB groups were 58.6 ± 4.7 and 14.5 ± 5.0 μg/ml, respectively (P < 0.01). In conclusion, the equilibrated blood sevoflurane concentrations showed a rapid decrease when switching from sevoflurane ventilation for the HL to CPB unless it was introduced to the oxygenator until completion of the switch.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).
言語 en
内容記述タイプ Other
出版者
言語 en
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.84.1.163
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/841.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 84, 号 1, p. 163-168, 発行日 2022-02
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