ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "fd292049-9bfd-4742-9918-af28e947169c"}, "_deposit": {"created_by": 17, "id": "2002703", "owner": "17", "owners": [17], "owners_ext": {"displayname": "repository", "username": "repository"}, "pid": {"revision_id": 0, "type": "depid", "value": "2002703"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:02002703", "sets": ["501"]}, "author_link": [], "control_number": "2002703", "item_1615768549627": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_1629683748249": {"attribute_name": "日付", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2023-04-01", "subitem_date_issued_type": "Available"}]}, "item_9_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2022-04", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "1716", "bibliographicPageStart": "1709", "bibliographicVolumeNumber": "61", "bibliographic_titles": [{"bibliographic_title": "Rheumatology", "bibliographic_titleLang": "en"}]}]}, "item_9_description_4": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "Objective: Anti-NOR90 antibodies are usually found in patients with SSc; however, their clinical relevance remains obscure. We developed an ELISA for measuring them to investigate the clinical features of patients with anti-NOR90 antibodies. Methods: Serum samples from 1252 patients with various conditions from Nagoya University Hospital and 244 patients with idiopathic interstitial pneumonia (IIP) from Tosei General Hospital were included. Anti-NOR90 antibodies were assayed by an ELISA using the recombinant protein produced by in vitro transcription/translation. Results: Five (0.4%) patients in the Nagoya University Hospital cohort had anti-NOR90 antibodies. One patient with diffuse cutaneous SSc, three with limited cutaneous SSc, and one with Raynaud’s disease were positive for anti-NOR90 antibodies. Anti-NOR90 antibodies were found more frequently in patients with systemic scleroderma-spectrum disorders (SSDs) than without SSDs (5/316 vs 0/936, P \u003c0.00101) and were found more frequently in patients with SSc than without SSc (4/249 vs 0/528, P \u003c0.0104) in the systemic autoimmune rheumatic diseases cohort. Three of the four anti-NOR90-positive SSc patients had interstitial lung disease (ILD), and two of those four had cancer. Three (1.2%) patients in the Tosei General Hospital cohort had anti-NOR90 antibodies. All three of the anti-NOR90-positive IIP patients had gastrointestinal tract involvement, and two of those three had cancer or skin lesions observed in SSc. Conclusions: Although anti-NOR90 antibodies are rarely found in clinics, our ELISA is useful for their detection. Further studies are needed to confirm the association of anti-NOR90 antibodies with ILD and cancer in SSc and IIP patients.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_9_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Oxford University Press", "subitem_publisher_language": "en"}]}, "item_9_relation_43": {"attribute_name": "関連情報", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1093/rheumatology/keab575", "subitem_relation_type_select": "DOI"}}]}, "item_9_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "This is a pre-copyedited, author-produced version of an article accepted for publication in [Rheumatology] following peer review. The version of record [Yuta Yamashita, Yasuhiko Yamano, Yoshinao Muro, Mariko Ogawa-Momohara, Takuya Takeichi, Yasuhiro Kondoh, Masashi Akiyama, Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia, Rheumatology, Volume 61, Issue 4, April 2022, Pages 1709–1716, https://doi.org/10.1093/rheumatology/keab575] is available online at: https://doi.org/10.1093/rheumatology/keab575.", "subitem_rights_language": "en"}]}, "item_9_source_id_7": {"attribute_name": "収録物識別子", "attribute_value_mlt": [{"subitem_source_identifier": "1462-0324", "subitem_source_identifier_type": "PISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "embargoed access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_f1cf"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yamashita, Yuta", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yamano, Yasuhiko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Muro, Yoshinao", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Ogawa-Momohara, Mariko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Takeichi, Takuya", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kondoh, Yasuhiro", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Akiyama, Masashi", "creatorNameLang": "en"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2023-04-01"}], "displaytype": "detail", "download_preview_message": "Download / Preview is available from 2023/3/31.", "file_order": 0, "filename": "RHE-21-1210_R1_Proof_hi.pdf", "filesize": [{"value": "908 KB"}], "format": "application/pdf", "future_date_message": "Download is available from 2023/3/31.", "is_thumbnail": false, "mimetype": "application/pdf", "size": 908000.0, "url": {"objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/2002703/files/RHE-21-1210_R1_Proof_hi.pdf"}, "version_id": "7b89c3d8-7973-4852-8b95-01de4d1e851b"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "anti-NOR90 antibody", "subitem_subject_scheme": "Other"}, {"subitem_subject": "anti-nucleolar antibody", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cancer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "idiopathic interstitial pneumonia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "interstitial lung disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "systemic autoimmune rheumatic disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "systemic sclerosis", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia", "subitem_title_language": "en"}]}, "item_type_id": "40001", "owner": "17", "path": ["501"], "permalink_uri": "http://hdl.handle.net/2237/0002002703", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2022-05-11"}, "publish_date": "2022-05-11", "publish_status": "0", "recid": "2002703", "relation": {}, "relation_version_is_last": true, "title": ["Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia"], "weko_shared_id": -1}
  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia

http://hdl.handle.net/2237/0002002703
http://hdl.handle.net/2237/0002002703
eb380027-b36a-4a14-9de6-1f99ef08027a
名前 / ファイル ライセンス アクション
RHE-21-1210_R1_Proof_hi.pdf RHE-21-1210_R1_Proof_hi.pdf (908 KB)
 Download is available from 2023/3/31.
Item type itemtype_ver1(1)
公開日 2022-05-11
タイトル
タイトル Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia
言語 en
著者 Yamashita, Yuta

× Yamashita, Yuta

en Yamashita, Yuta

Search repository
Yamano, Yasuhiko

× Yamano, Yasuhiko

en Yamano, Yasuhiko

Search repository
Muro, Yoshinao

× Muro, Yoshinao

en Muro, Yoshinao

Search repository
Ogawa-Momohara, Mariko

× Ogawa-Momohara, Mariko

en Ogawa-Momohara, Mariko

Search repository
Takeichi, Takuya

× Takeichi, Takuya

en Takeichi, Takuya

Search repository
Kondoh, Yasuhiro

× Kondoh, Yasuhiro

en Kondoh, Yasuhiro

Search repository
Akiyama, Masashi

× Akiyama, Masashi

en Akiyama, Masashi

Search repository
アクセス権
アクセス権 embargoed access
アクセス権URI http://purl.org/coar/access_right/c_f1cf
権利
言語 en
権利情報 This is a pre-copyedited, author-produced version of an article accepted for publication in [Rheumatology] following peer review. The version of record [Yuta Yamashita, Yasuhiko Yamano, Yoshinao Muro, Mariko Ogawa-Momohara, Takuya Takeichi, Yasuhiro Kondoh, Masashi Akiyama, Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia, Rheumatology, Volume 61, Issue 4, April 2022, Pages 1709–1716, https://doi.org/10.1093/rheumatology/keab575] is available online at: https://doi.org/10.1093/rheumatology/keab575.
キーワード
主題Scheme Other
主題 anti-NOR90 antibody
キーワード
主題Scheme Other
主題 anti-nucleolar antibody
キーワード
主題Scheme Other
主題 cancer
キーワード
主題Scheme Other
主題 idiopathic interstitial pneumonia
キーワード
主題Scheme Other
主題 interstitial lung disease
キーワード
主題Scheme Other
主題 systemic autoimmune rheumatic disease
キーワード
主題Scheme Other
主題 systemic sclerosis
内容記述
内容記述 Objective: Anti-NOR90 antibodies are usually found in patients with SSc; however, their clinical relevance remains obscure. We developed an ELISA for measuring them to investigate the clinical features of patients with anti-NOR90 antibodies. Methods: Serum samples from 1252 patients with various conditions from Nagoya University Hospital and 244 patients with idiopathic interstitial pneumonia (IIP) from Tosei General Hospital were included. Anti-NOR90 antibodies were assayed by an ELISA using the recombinant protein produced by in vitro transcription/translation. Results: Five (0.4%) patients in the Nagoya University Hospital cohort had anti-NOR90 antibodies. One patient with diffuse cutaneous SSc, three with limited cutaneous SSc, and one with Raynaud’s disease were positive for anti-NOR90 antibodies. Anti-NOR90 antibodies were found more frequently in patients with systemic scleroderma-spectrum disorders (SSDs) than without SSDs (5/316 vs 0/936, P <0.00101) and were found more frequently in patients with SSc than without SSc (4/249 vs 0/528, P <0.0104) in the systemic autoimmune rheumatic diseases cohort. Three of the four anti-NOR90-positive SSc patients had interstitial lung disease (ILD), and two of those four had cancer. Three (1.2%) patients in the Tosei General Hospital cohort had anti-NOR90 antibodies. All three of the anti-NOR90-positive IIP patients had gastrointestinal tract involvement, and two of those three had cancer or skin lesions observed in SSc. Conclusions: Although anti-NOR90 antibodies are rarely found in clinics, our ELISA is useful for their detection. Further studies are needed to confirm the association of anti-NOR90 antibodies with ILD and cancer in SSc and IIP patients.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Oxford University Press
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1093/rheumatology/keab575
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 1462-0324
書誌情報 en : Rheumatology

巻 61, 号 4, p. 1709-1716, 発行日 2022-04
ファイル公開日
日付 2023-04-01
日付タイプ Available
戻る
0
views
See details
Views

Versions

Ver.1 2022-05-11 02:03:09.528675
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3