| Item type |
itemtype_ver1(1) |
| 公開日 |
2022-05-27 |
| タイトル |
|
|
タイトル |
Clinical characteristics and risk factors for mortality in patients with community-acquired staphylococcal pneumonia |
|
言語 |
en |
| 著者 |
Thabet, Nancy
Shindo, Yuichiro
Okumura, Junya
Sano, Masahiro
Sakakibara, Toshihiro
Murakami, Yasushi
Kobayashi, Hironori
Saka, Hideo
Kondo, Masashi
Hasegawa, Yoshinori
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利 |
|
|
言語 |
en |
|
権利情報Resource |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
権利情報 |
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Staphylococcus aureus |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
community-acquired pneumonia |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
pneumococcal pneumonia |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
clinical characteristics |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
mortality |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Staphylococcus aureus (S. aureus) is increasing in prevalence as a causative pathogen of community-acquired pneumonia (CAP). However, reports on the clinical features and mortality risk factors for S. aureus CAP are limited. We therefore aimed to identify the clinical characteristics and risk factors for mortality in these patients. We performed a post hoc and multivariate analysis of a multicenter prospective observational study that included adult hospitalized patients with S. aureus CAP. To elucidate the features of S. aureus CAP, we comparatively analyzed pneumococcal CAP (PCAP). We analyzed 196 patients with S. aureus CAP and 198 patients with PCAP. S. aureus CAP had a 30-day mortality of 16% (31/196) and a higher frequency of factors such as advanced age, comorbidities, poor functional ability, altered mental status, hypoalbuminemia, hyponatremia/hypernatremia, acidemia, and hypoxemia. In the multivariate analysis, the significant risk factors for mortality in S. aureus CAP were PaO2/FiO2 ≤250 [adjusted odds ratio (AOR), 3.29; 95% confidence interval (CI), 1.20–9.04] and albumin <3.0 g/dL (AOR, 2.41; 95% CI, 1.01–5.83). Non-ambulatory status tended to increase the risk (AOR, 2.40; 95% CI, 0.93–6.17). Methicillin resistance was not associated with mortality. In PCAP, hypoalbuminemia and non-ambulatory status affected mortality but hypoxemia did not. In conclusion, patients with S. aureus CAP have distinct clinical features, and their mortality risk factors can include hypoxemia and hypoalbuminemia. Physicians should recognize that the factors influencing mortality might differ somewhat among causative pathogens, and appropriate management should be performed after obtaining information on the causative pathogen. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Nagoya University Graduate School of Medicine, School of Medicine |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| ID登録 |
|
|
ID登録 |
10.18999/nagjms.84.2.247 |
|
ID登録タイプ |
JaLC |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/842.html |
| 収録物識別子 |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0027-7622 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2186-3326 |
| 書誌情報 |
en : Nagoya Journal of Medical Science
巻 84,
号 2,
p. 247-259,
発行日 2022-05
|
04_Thabet.pdf (947 KB)
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