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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 84(3)

Association between serum carotenoids and premature mortality in a population-based case-control study

https://doi.org/10.18999/nagjms.84.3.607
https://doi.org/10.18999/nagjms.84.3.607
cfbd11b8-40e3-43a3-a854-d349f3837d63
名前 / ファイル ライセンス アクション
12_Fujii.pdf 12_Fujii.pdf (473 KB)
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Item type itemtype_ver1(1)
公開日 2022-09-05
タイトル
タイトル Association between serum carotenoids and premature mortality in a population-based case-control study
言語 en
著者 Fujii, Ryosuke

× Fujii, Ryosuke

en Fujii, Ryosuke

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Suzuki, Koji

× Suzuki, Koji

en Suzuki, Koji

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Yamada, Hiroya

× Yamada, Hiroya

en Yamada, Hiroya

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Kawado, Miyuki

× Kawado, Miyuki

en Kawado, Miyuki

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Hashimoto, Shuji

× Hashimoto, Shuji

en Hashimoto, Shuji

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Tsuboi, Yoshiki

× Tsuboi, Yoshiki

en Tsuboi, Yoshiki

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Wakai, Kenji

× Wakai, Kenji

en Wakai, Kenji

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Iso, Hiroyasu

× Iso, Hiroyasu

en Iso, Hiroyasu

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Watanabe, Yoshiyuki

× Watanabe, Yoshiyuki

en Watanabe, Yoshiyuki

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Fujino, Yoshihisa

× Fujino, Yoshihisa

en Fujino, Yoshihisa

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Tamakoshi, Akiko

× Tamakoshi, Akiko

en Tamakoshi, Akiko

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JACC Study Group

× JACC Study Group

en JACC Study Group

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報Resource http://creativecommons.org/licenses/by-nc-nd/4.0/
権利情報 Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
キーワード
主題Scheme Other
主題 carotenoid
キーワード
主題Scheme Other
主題 premature mortality
キーワード
主題Scheme Other
主題 case-control study
キーワード
主題Scheme Other
主題 cancer mortality
キーワード
主題Scheme Other
主題 epidemiology
内容記述
内容記述 Carotenoids are abundant pigments mainly contained in vegetables and fruits, and show antioxidant properties by quenching free radicals in human body. Few studies have investigated associations between serum carotenoid levels and premature mortality. The objective of this study was to investigate the association between serum carotenoid level and premature mortality in a Japanese population. This study included 446 Japanese adults (174 men, aged of 40–64) recruited as participants in the Japan Collaborative Cohort (JACC) Study. Serum carotenoid level was measured by high-performance liquid chromatography. Premature mortality was defined as death before 65 years old during the follow-up period. Premature mortality was ascertained in 60 men (34.5%) and 65 women (23.9%). In men, compared to the 1st tertile of serum b-cryptoxanthin and provitamin A, those who were in the 3rd tertile had lower risks of premature all-cause mortality (OR, 95% CI: 0.19, 0.07–0.47 for b-cryptoxanthin, and 0.24, 0.09–0.61 for provitamin A). In women, compared to the 1st tertile of serum b-cryptoxanthin, those who were in the 3rd tertile had higher risks of premature all-cause mortality (OR, 95% CI: 1.94, 1.00–4.03). These significant associations were observed in analyses for premature cancer mortality. We found significant associations between higher levels of serum b-cryptoxanthin and provitamin A and lower risks of premature mortality among Japanese men, while a different directional association was found in women. Although these findings suggest roles of serum carotenoids on premature mortality, further studies are needed to validate this association in other populations.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.84.3.607
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/843.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 84, 号 3, p. 607-620, 発行日 2022-08
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