| Item type |
itemtype_ver1(1) |
| 公開日 |
2022-09-05 |
| タイトル |
|
|
タイトル |
Association between serum carotenoids and premature mortality in a population-based case-control study |
|
言語 |
en |
| 著者 |
Fujii, Ryosuke
Suzuki, Koji
Yamada, Hiroya
Kawado, Miyuki
Hashimoto, Shuji
Tsuboi, Yoshiki
Wakai, Kenji
Iso, Hiroyasu
Watanabe, Yoshiyuki
Fujino, Yoshihisa
Tamakoshi, Akiko
JACC Study Group
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利 |
|
|
言語 |
en |
|
権利情報Resource |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
権利情報 |
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
carotenoid |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
premature mortality |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
case-control study |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
cancer mortality |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
epidemiology |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Carotenoids are abundant pigments mainly contained in vegetables and fruits, and show antioxidant properties by quenching free radicals in human body. Few studies have investigated associations between serum carotenoid levels and premature mortality. The objective of this study was to investigate the association between serum carotenoid level and premature mortality in a Japanese population. This study included 446 Japanese adults (174 men, aged of 40–64) recruited as participants in the Japan Collaborative Cohort (JACC) Study. Serum carotenoid level was measured by high-performance liquid chromatography. Premature mortality was defined as death before 65 years old during the follow-up period. Premature mortality was ascertained in 60 men (34.5%) and 65 women (23.9%). In men, compared to the 1st tertile of serum b-cryptoxanthin and provitamin A, those who were in the 3rd tertile had lower risks of premature all-cause mortality (OR, 95% CI: 0.19, 0.07–0.47 for b-cryptoxanthin, and 0.24, 0.09–0.61 for provitamin A). In women, compared to the 1st tertile of serum b-cryptoxanthin, those who were in the 3rd tertile had higher risks of premature all-cause mortality (OR, 95% CI: 1.94, 1.00–4.03). These significant associations were observed in analyses for premature cancer mortality. We found significant associations between higher levels of serum b-cryptoxanthin and provitamin A and lower risks of premature mortality among Japanese men, while a different directional association was found in women. Although these findings suggest roles of serum carotenoids on premature mortality, further studies are needed to validate this association in other populations. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Nagoya University Graduate School of Medicine, School of Medicine |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| ID登録 |
|
|
ID登録 |
10.18999/nagjms.84.3.607 |
|
ID登録タイプ |
JaLC |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/843.html |
| 収録物識別子 |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0027-7622 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2186-3326 |
| 書誌情報 |
en : Nagoya Journal of Medical Science
巻 84,
号 3,
p. 607-620,
発行日 2022-08
|
12_Fujii.pdf (473 KB)
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