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We synthesized a Tschimganine analog, Mochimganine, which extends the lifespan similar to Tschimganine but exhibits a significantly weaker growth inhibition effect. Based on the comparative analysis of these compounds, we propose that Tschimganine has at least 2 targets: one extends the lifespan and the other inhibits growth.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Oxford University Press", "subitem_publisher_language": "en"}]}, "item_9_relation_43": {"attribute_name": "\u95a2\u9023\u60c5\u5831", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1093/bbb/zbac051", "subitem_relation_type_select": "DOI"}}]}, "item_9_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "This is a pre-copyedited, author-produced version of an article accepted for publication in [Bioscience, Biotechnology, and Biochemistry] following peer review. The version of record [Hokuto Ohtsuka, Takuma Matsumoto, Takahiro Mochida, Takafumi Shimasaki, Masatoshi Shibuya, Yoshihiko Yamamoto, Hirofumi Aiba, Tschimganine has different targets for chronological lifespan extension and growth inhibition in fission yeast, Bioscience, Biotechnology, and Biochemistry, Volume 86, Issue 6, June 2022, Pages 775\u2013779, https://doi.org/10.1093/bbb/zbac051] is available online at: https://doi.org/10.1093/bbb/zbac051.", "subitem_rights_language": "en"}]}, "item_9_source_id_7": {"attribute_name": "\u53ce\u9332\u7269\u8b58\u5225\u5b50", "attribute_value_mlt": [{"subitem_source_identifier": "0916-8451", "subitem_source_identifier_type": "PISSN"}]}, "item_access_right": {"attribute_name": "\u30a2\u30af\u30bb\u30b9\u6a29", "attribute_value_mlt": [{"subitem_access_right": "embargoed access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_f1cf"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ohtsuka, Hokuto", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Matsumoto, Takuma", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Mochida, Takahiro", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Shimasaki, Takafumi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Shibuya, Masatoshi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Yoshihiko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Aiba, Hirofumi", "creatorNameLang": "en"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2022-09-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "BBB-220049.R1.pdf", "filesize": [{"value": "5.4 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "application/pdf", "size": 5400000.0, "url": {"objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/2003773/files/BBB-220049.R1.pdf"}, "version_id": "e5b632c2-cdeb-4964-88dc-529ca67f548a"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Tschimganine", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Mochimganine", "subitem_subject_scheme": "Other"}, {"subitem_subject": "chronological lifespan", "subitem_subject_scheme": "Other"}, {"subitem_subject": "fission yeast", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Tschimganine has different targets for chronological lifespan extension and growth inhibition in fission yeast", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Tschimganine has different targets for chronological lifespan extension and growth inhibition in fission yeast", "subitem_title_language": "en"}]}, "item_type_id": "40001", "owner": "17", "path": ["1903/1904/1905"], "permalink_uri": "http://hdl.handle.net/2237/0002003773", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2022-09-13"}, "publish_date": "2022-09-13", "publish_status": "0", "recid": "2003773", "relation": {}, "relation_version_is_last": true, "title": ["Tschimganine has different targets for chronological lifespan extension and growth inhibition in fission yeast"], "weko_shared_id": -1}