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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 84(4)

Analysis of immunologic comorbidities in ulcerative colitis patients: a tool to prevent exacerbations in ulcerative colitis cases

https://doi.org/10.18999/nagjms.84.4.733
https://doi.org/10.18999/nagjms.84.4.733
3ae9a249-dec3-4dba-9e40-d8b8ebd45598
名前 / ファイル ライセンス アクション
05_RodriquezMeza.pdf 05_RodriquezMeza.pdf (676 KB)
license.icon
Item type itemtype_ver1(1)
公開日 2022-11-22
タイトル
タイトル Analysis of immunologic comorbidities in ulcerative colitis patients: a tool to prevent exacerbations in ulcerative colitis cases
言語 en
著者 Rodríguez Meza, Miguel Ricardo

× Rodríguez Meza, Miguel Ricardo

en Rodríguez Meza, Miguel Ricardo

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Nakamura, Masanao

× Nakamura, Masanao

en Nakamura, Masanao

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Yamamura, Takeshi

× Yamamura, Takeshi

en Yamamura, Takeshi

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Maeda, Keiko

× Maeda, Keiko

en Maeda, Keiko

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Sawada, Tsunaki

× Sawada, Tsunaki

en Sawada, Tsunaki

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Ishikawa, Eri

× Ishikawa, Eri

en Ishikawa, Eri

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Kakushima, Naomi

× Kakushima, Naomi

en Kakushima, Naomi

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Furukawa, Kazuhiro

× Furukawa, Kazuhiro

en Furukawa, Kazuhiro

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Iida, Tadashi

× Iida, Tadashi

en Iida, Tadashi

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Mizutani, Yasuyuki

× Mizutani, Yasuyuki

en Mizutani, Yasuyuki

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Ishikawa, Takuya

× Ishikawa, Takuya

en Ishikawa, Takuya

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Ohno, Eizaburo

× Ohno, Eizaburo

en Ohno, Eizaburo

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Honda, Takashi

× Honda, Takashi

en Honda, Takashi

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Kawashima, Hiroki

× Kawashima, Hiroki

en Kawashima, Hiroki

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Ishigami, Masatoshi

× Ishigami, Masatoshi

en Ishigami, Masatoshi

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
主題Scheme Other
主題 ulcerative colitis
キーワード
主題Scheme Other
主題 Crohn’s disease
キーワード
主題Scheme Other
主題 inflammatory bowel disease
キーワード
主題Scheme Other
主題 extra-intestinal manifestations
キーワード
主題Scheme Other
主題 comorbidity
内容記述
内容記述 There have been previous studies, especially in Western countries and even in some areas in Asia, about extra-intestinal manifestations (EIMs) and its link with the outcome of inflammatory bowel disease (IBD), which includes Crohn’s disease (CD), and ulcerative colitis (UC). This link is crucial when discussing a patient’s prognosis and important when dealing with UC management. The aim of this study was to clarify the most common comorbidities associated with UC, emphasizing immunologic comorbidities in Japan. This study was a retrospective analysis performed at Nagoya University Hospital. The data collection started in March, 2019, and continued for two years. We retrieved the medical records of 105 patients with UC diagnosis, from which the data of 176 EIMs were extracted and analyzed. Results showed that EIMs with UC in the active phase accounted for 43.7% of total EIMs. Twenty-six patients with immune-mediated inflammatory disease frequently had an active phase (odds ratio [OR] 3.84, 99% CI, 1.44–10.27). Comorbidities showing an active manifestation of symptoms and UC in the active phase were significantly correlated in patients with immunological comorbidities, such as peripheral arthritis (r = 0.97, p < 0.01) and rheumatoid arthritis (RA) (r = 0.99, p < 0.01), as well as in patients with primary sclerosis cholangitis (PSC) (r = 0.98, p < 0.01). In conclusion, this analysis suggests the importance of having full comprehension of how immunological comorbidities affect the natural development of UC, which is of vital importance to prevent further UC complications and properly adjust the management of the disease.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.84.4.733
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/844.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 84, 号 4, p. 733-745, 発行日 2022-11
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