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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 84(4)

Primary laryngeal cryptococcosis mimicking laryngeal malignancy: a case report

https://doi.org/10.18999/nagjms.84.4.900
https://doi.org/10.18999/nagjms.84.4.900
ff2824d6-bc2d-4a04-95e5-f796e251e2f4
名前 / ファイル ライセンス アクション
22_Tonai.pdf 22_Tonai.pdf (21.3 MB)
license.icon
Item type itemtype_ver1(1)
公開日 2022-11-22
タイトル
タイトル Primary laryngeal cryptococcosis mimicking laryngeal malignancy: a case report
言語 en
著者 Tonai, Kazuya

× Tonai, Kazuya

en Tonai, Kazuya

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Nishio, Naoki

× Nishio, Naoki

en Nishio, Naoki

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Yokoi, Sayaka

× Yokoi, Sayaka

en Yokoi, Sayaka

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Kobayashi, Masumi

× Kobayashi, Masumi

en Kobayashi, Masumi

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Sone, Michihiko

× Sone, Michihiko

en Sone, Michihiko

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
主題Scheme Other
主題 laryngeal cryptococcosis
キーワード
主題Scheme Other
主題 yeast-like fungus
キーワード
主題Scheme Other
主題 Alcian blue stain
キーワード
主題Scheme Other
主題 fluconazole
キーワード
主題Scheme Other
主題 inhaled corticosteroid
内容記述
内容記述 Primary laryngeal cryptococcosis is an extremely rare infection and presents with non-specific symptoms such as hoarseness or sore throat, resulting in delayed diagnosis. Here, we report the patient of a 56-year-old female patient with primary laryngeal cryptococcosis, who was being treated with oral and inhaled steroids for rheumatoid arthritis and bronchial asthma. The patient suffered from prolonged hoarseness and sore throat, and endoscopic biopsy was performed several times under local anesthesia, demonstrating only inflammatory cell infiltration. Considering the possibility of laryngeal malignancy, a third biopsy was performed by endoscopic laryngomicrosurgery under general anesthesia. Intraoperative frozen section revealed non-neoplastic laryngeal mucosa with erosion and severe inflammatory cell infiltration. However, we could not confirm the definite diagnosis of the lesion in the intraoperative consultation. Postoperative histopathological examination revealed a small number of yeast-type fungi and a definitive diagnosis was established by special stains including Alcian blue stain. Finally, the patient was diagnosed as primary laryngeal cryptococcosis. Daily oral administration of fluconazole (400 mg/day) was performed for 6 months according to the treatment protocol for pulmonary cryptococcosis. The symptoms gradually improved, and endoscopy revealed no recurrence 6 months post-treatment. Clinicians should consider the possibility of laryngeal cryptococcosis when severe inflammation is found in the larynx and discuss the disease history and pathological results with pathologists more closely.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.84.4.900
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/844.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 84, 号 4, p. 900-905, 発行日 2022-11
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