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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Factors associated with the progression of myosteatosis in patients with cirrhosis

http://hdl.handle.net/2237/0002004244
http://hdl.handle.net/2237/0002004244
0ace45d6-a9b6-4b82-8e48-06e01a7b9b5a
名前 / ファイル ライセンス アクション
Title_and_Manuscript.pdf Title_and_Manuscript.pdf (251 KB)
Figure1.pdf Figure1.pdf (39 KB)
Figure2.pdf Figure2.pdf (57 KB)
Figure3.pdf Figure3.pdf (58 KB)
Item type itemtype_ver1(1)
公開日 2022-12-01
タイトル
タイトル Factors associated with the progression of myosteatosis in patients with cirrhosis
言語 en
著者 Ishizu, Yoji

× Ishizu, Yoji

en Ishizu, Yoji

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Ishigami, Masatoshi

× Ishigami, Masatoshi

en Ishigami, Masatoshi

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Honda, Takashi

× Honda, Takashi

en Honda, Takashi

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Imai, Norihiro

× Imai, Norihiro

en Imai, Norihiro

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Ito, Takanori

× Ito, Takanori

en Ito, Takanori

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Yamamoto, Kenta

× Yamamoto, Kenta

en Yamamoto, Kenta

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Yokoyama, Shinya

× Yokoyama, Shinya

en Yokoyama, Shinya

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Ishikawa, Tetsuya

× Ishikawa, Tetsuya

en Ishikawa, Tetsuya

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Fujishiro, Mitsuhiro

× Fujishiro, Mitsuhiro

en Fujishiro, Mitsuhiro

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 © 2022. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
内容記述
内容記述タイプ Abstract
内容記述 Objectives: The presence of myosteatosis is one factor associated with poor prognosis for patients with cirrhosis; however, the factors contributing to worsening myosteatosis are, to our knowledge, unknown. The aim of this study was to clarify the changes in myosteatosis, and the factors involved in these changes. Methods: The present study enrolled 178 patients with cirrhosis who underwent computed tomography twice to measure changes in skeletal muscle attenuation (SMA) at the L3 level. Factors associated with SMA and those associated with changes in SMA were examined. Results: Using linear multiple regression analysis, age (β = –0.22), skeletal muscle index (SMI; skeletal muscle area divided by height squared; β = 0.25), and visceral and subcutaneous fat indices (VFI and SFI; the visceral and subcutaneous fat areas at the umbilical level divided by height squared; β = –0.08, β = –0.06, respectively) were identified as associated with SMA. The 100-d change in SMA was –0.21 ± 1.29 Hounsfield units (HU). Changes in SMI and SMA were positively associated (R = 0.183, P = 0.014), whereas those in VFI and SMA were negatively associated (R = –0.172, P = 0.022). No association was noted between the 100-d changes in SFI and SMA. In patients whose SMI increased and VFI decreased, the 100-d change in SMA was 0.24 ± 1.82 HU, which was marginally different from that in patients whose SMI decreased and VFI increased (–0.44 ± 1.32 HU, P = 0.077). Conclusions: In patients with cirrhosis, myosteatosis progressed, and decreases in SMI and increases in VFI were correlated with its progression.
言語 en
出版者
出版者 Elsevier
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.nut.2022.111777
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 08999007
書誌情報 en : Nutrition

巻 103-104, p. 111777, 発行日 2022-11
ファイル公開日
日付 2023-11-01
日付タイプ Available
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