Item type |
itemtype_ver1(1) |
公開日 |
2023-04-18 |
タイトル |
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タイトル |
骨格筋におけるケトン体代謝に関する研究(第3報) : 12Hz刺激による連動筋でのケトン体変動 |
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言語 |
ja |
その他のタイトル |
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その他のタイトル |
Ketone body metabolism in muscle (III) : Changes in keton body concentration in the 12 Hz-stimulated muscle |
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言語 |
en |
著者 |
楊, 衛平
押田, 芳治
呉, 瑋
佐藤, 寿一
大沢, 功
佐藤, 祐造
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Physical training has been shown to improve insulin action in simple obese and obese diabetic patients. On the other hand,the hyperketonemic effect of prolonged exercise in insulin-dependent diabetic patients is well recognized phenomenon. Recently, we have demonstrated that 60-min high-frequency (60Hz) stimulation produces a significant reduction in 3-hydroxybutyrate (3-OHBA) uptake in muscle not only in diabetic but also in control rats and that a reduction in 3-OHBA utilization in diabetics is found for 90 min after muscle constriction. In the present study. we measured extracellular 3-OHBA concentrations in 12Hz-stimulated muscle for five diabetic and five control rats by use of the microdialysis technique. The following results were obtained: 1. In control rats, there was no significant difference in 3-OHBA levels between before, during and after stimulation. 2. In diabetics, the dialysate 3-OHBA concentrations showed a significant increase during constriction and for 90 min after constriction. It is well known that 12Hz-stimuli is more aerobic in muscle than 60-Hz-stimuli. Therefore, it may be advisable that diabetic patients performe an aerobic exercise, in order to increase insulin action in peripheral tissue, after nearly normalization for metabolism by diet and insulin therapy, and so on. |
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言語 |
en |
出版者 |
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出版者 |
名古屋大学総合保健体育科学センター |
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言語 |
ja |
出版者 |
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出版者 |
The Research Center of Health, Physical Fitness and Sports, Nagoya University |
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言語 |
en |
言語 |
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言語 |
jpn |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
departmental bulletin paper |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
ID登録 |
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ID登録 |
10.18999/njhpfs.17.1.13 |
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ID登録タイプ |
JaLC |
収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0289-5412 |
書誌情報 |
ja : 総合保健体育科学
en : Nagoya Journal of Health, Physical Fitness & Sports
巻 17,
号 1,
p. 13-16,
発行日 1994-03-30
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