Item type |
itemtype_ver1(1) |
公開日 |
2023-06-13 |
タイトル |
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タイトル |
Pathological gait in Rett syndrome: Quantitative evaluation using three-dimensional gait analysis |
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言語 |
en |
著者 |
Suzuki, Takeshi
Ito, Yuji
Ito, Tadashi
Kidokoro, Hiroyuki
Noritake, Koji
Tsujimura, Keita
Saitoh, Shinji
Yamamoto, Hiroyuki
Ochi, Nobuhiko
Ishihara, Naoko
Yasui, Izumi
Sugiura, Hideshi
Nakata, Tomohiko
Natsume, Jun
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利 |
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言語 |
en |
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権利情報 |
© 2023. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
キーワード |
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主題Scheme |
Other |
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主題 |
Rett syndrome |
キーワード |
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主題Scheme |
Other |
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主題 |
Three-dimensional gait analysis |
キーワード |
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主題Scheme |
Other |
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主題 |
Ataxic-rigid gait |
キーワード |
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主題Scheme |
Other |
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主題 |
Dystonia |
内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Objectives: Ataxic-rigid gait is a characteristic gait pathology in patients with Rett syndrome (RTT). In the present study, we aimed to quantitatively evaluate gait pathology in patients with RTT using three-dimensional gait analysis (3DGA). Methods: We performed 3DGA in 11 patients with RTT ranging from 5 to 18 years (median age, 9 years) and in 33 age-matched healthy female controls. We compared the results of 3DGA, including spatiotemporal gait parameters and comprehensive indices of gait kinematics, such as the Gait Deviation Index (GDI) and Gait Profile Score (GPS), between the two groups. The GPS consists of nine sub-indices called Gait Variable Scores (GVSs). Decline in GDI or elevation of GPS and GVS indicated greater abnormal gait pathology. Results: The patients demonstrated significantly slower walking speed, lower step length/length of the lower extremities, lower cadence, wider step width, and higher coefficient of variation of step length than the controls. Moreover, the patients had a lower GDI and higher GPS than the controls. The patients also exhibited higher GVSs for eight out of nine gait kinematics, particularly the sagittal plane in the pelvis, hip, knee, and ankle joint; coronal plane in the pelvis and hip joint; and horizontal plane in the pelvis than the controls. Conclusions: Quantitative evaluation of gait pathology in patients with RTT is possible using 3DGA. We found that in addition to ataxic-rigid gait, abnormalities in the coronal plane of the pelvis and hip joint and the horizontal plane of the pelvis were prominent. |
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言語 |
en |
出版者 |
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出版者 |
Elsevier |
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言語 |
en |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
関連情報 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.ejpn.2022.11.010 |
収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
10903798 |
書誌情報 |
en : European Journal of Paediatric Neurology
巻 42,
p. 15-21,
発行日 2023-01
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ファイル公開日 |
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日付 |
2024-01-01 |
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日付タイプ |
Available |