Item type |
itemtype_ver1(1) |
公開日 |
2023-06-15 |
タイトル |
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タイトル |
Which modality is better to diagnose high-grade transformation in retroperitoneal liposarcoma? Comparison of computed tomography, positron emission tomography, and magnetic resonance imaging |
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言語 |
en |
著者 |
Nakashima, Yu
Yokoyama, Yukihiro
Ogawa, Hiroshi
Sakakibara, Ayako
Sunagawa, Masaki
Nishida, Yoshihiro
Mizuno, Takashi
Yamaguchi, Junpei
Onoe, Shunsuke
Watanabe, Nobuyuki
Kawakatsu, Shoji
Igami, Tsuyoshi
Ebata, Tomoki
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利 |
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言語 |
en |
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権利情報 |
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10147-022-02287-6 |
キーワード |
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主題Scheme |
Other |
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主題 |
Retroperitoneal liposarcoma |
キーワード |
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主題Scheme |
Other |
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主題 |
Differentiation |
キーワード |
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主題Scheme |
Other |
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主題 |
Imaging analysis |
キーワード |
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主題Scheme |
Other |
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主題 |
18F-fluorodeoxyglucose positron emission tomography |
キーワード |
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主題Scheme |
Other |
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主題 |
Diffusion-weighted MRI |
内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background: Survival in patients with retroperitoneal liposarcoma (RPLS) depends on the surgical management of the dedifferentiated foci. The present study investigated the diagnostic yield of contrast-enhanced CT, 18F-fluorodeoxyglucose positron emission tomography (PET), and diffusion-weighted MRI in terms of dedifferentiated foci within the RPLS. Methods: Patients treated with primary or recurrent RPLS who underwent the above imaging between January 2010 and December 2021 were retrospectively reviewed. The diagnostic accuracy of the three modalities for histologic subtype of dedifferentiated liposarcoma (DDLS) and French Federation of Cancer Center (FNCLCC) grade 2/3 were compared using receiver operating characteristic curves and areas under the curves (AUCs). Results: The cohort involved 32 patients with 53 tumors; 30 of which exhibited DDLS and 31 of which did FNCLCC grades 2/3. The optimal thresholds for predicting DDLS were mean CT value of 31 Hounsfield Unit (HU) (AUC = 0.880, 95% CI 0.775–0.984; p < 0.001), maximum standardized uptake value (SUVmax) of 2.9 (AUC = 0.865 95% CI 0.792–0.980; p < 0.001), while MRI failed to differentiate DDLS. The cutoff values for distinguishing FNCLCC grades 1 and 2/3 were a mean CT value of 24 HU (AUC = 0.858, 95% CI 0.731–0.985; p < 0.001) and SUVmax of 2.9 (AUC = 0.885, 95% CI 0.792–0.978; p < 0.001). MRI had no sufficient power to separate these grades. Conclusions: Contrast-enhanced CT and PET were useful for predicting DDLS and FNCLCC grade 2/3, while MRI was inferior to these two modalities. |
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言語 |
en |
出版者 |
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出版者 |
Springer |
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言語 |
en |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
関連情報 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1007/s10147-022-02287-6 |
収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1341-9625 |
書誌情報 |
en : International Journal of Clinical Oncology
巻 28,
号 3,
p. 482-490,
発行日 2023-03
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ファイル公開日 |
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日付 |
2024-03-01 |
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日付タイプ |
Available |