Item type |
itemtype_ver1(1) |
公開日 |
2023-08-30 |
タイトル |
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タイトル |
Comparison of clinical features between patients with acute exacerbation of idiopathic interstitial pneumonia and collagen vascular disease-associated interstitial pneumonia |
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言語 |
en |
著者 |
Kata, Yuki
Hara, Yu
Murohashi, Kota
Saigusa, Yusuke
Nagasawa, Ryo
Tagami, Yoichi
Fujii, Hiroaki
Aoki, Ayako
Nishikawa, Yurika
Tanaka, Katsushi
Watanabe, Keisuke
Horita, Nobuyuki
Kobayashi, Nobuaki
Yamamoto, Masaki
Kudo, Makoto
Kaneko, Takeshi
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利 |
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言語 |
en |
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権利情報Resource |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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権利情報 |
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International |
キーワード |
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主題Scheme |
Other |
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主題 |
acute exacerbation |
キーワード |
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主題Scheme |
Other |
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主題 |
Charlson Comorbidity Index score |
キーワード |
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主題Scheme |
Other |
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主題 |
collagen vascular disease-associated interstitial pneumonia |
キーワード |
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主題Scheme |
Other |
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主題 |
idiopathic interstitial pneumonia |
キーワード |
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主題Scheme |
Other |
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主題 |
lactate dehydrogenase |
内容記述 |
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内容記述 |
Acute exacerbation (AE) of interstitial pneumonia (IP) shows poor prognosis, due to the typical histological pattern of diffuse alveolar damage superimposed upon lung fibrosis. The previous reports comparing clinical features between AE of idiopathic interstitial pneumonias (IIPs) and those of IPs with known etiology are limited. We retrospectively compared clinical parameters including age, sex, Charlson Comorbidity Index score (CCIS), blood biomarkers at diagnosis of AE, treatment, and 3-month mortality between patients with AE of IIPs and collagen vascular disease-associated interstitial pneumonia (CVD-IP). We assessed 85 patients, comprising 66 patients with AE of IIPs (78%) and 19 patients with AE of CVD-IP (22%). The least absolute shrinkage and selection operator regression selected CCIS (hazard ratio, 1.281; 95% confidence interval, 1.055–1.556; P = 0.012) and log serum lactate dehydrogenase (LDH) (hazard ratio, 6.267; 95% confidence interval, 2.172–18.085; P < 0.001) as significant predictors of 3-month mortality among these patients. Also, the adjusted survival curves using sex, CCIS, and serum LDH showed no significant differences between these two groups. In conclusion, among AE patients, CCIS and serum LDH level may be more important prognostic factors for 3-month mortality rather than two classification of IP subtypes: IIPs and CVD-IP. |
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言語 |
en |
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内容記述タイプ |
Abstract |
出版者 |
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言語 |
en |
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出版者 |
Nagoya University Graduate School of Medicine, School of Medicine |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
departmental bulletin paper |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
ID登録 |
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ID登録 |
10.18999/nagjms.85.3.602 |
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ID登録タイプ |
JaLC |
関連情報 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
URI |
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関連識別子 |
https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/853.html |
収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0027-7622 |
収録物識別子 |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2186-3326 |
書誌情報 |
en : Nagoya Journal of Medical Science
巻 85,
号 3,
p. 602-611,
発行日 2023-08
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