Item type |
itemtype_ver1(1) |
公開日 |
2024-04-22 |
タイトル |
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タイトル |
Extremely Low Frequency, Extremely Low Magnetic Environment for depression: An open-label trial |
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言語 |
en |
著者 |
Tachibana, Masako
Inada, Toshiya
Kimura, Hiroki
Ito, Mikako
Kuwatsuka, Yachiyo
Kinoshita, Fumie
Mori, Daisuke
Ohno, Kinji
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アクセス権 |
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アクセス権 |
embargoed access |
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アクセス権URI |
http://purl.org/coar/access_right/c_f1cf |
権利 |
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言語 |
en |
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権利情報 |
© 2024. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
内容記述 |
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内容記述 |
Mitochondrial dysfunction has been suggested to play a role in depression pathogenesis. This clinical trial (jRCTs042220011) was conducted to evaluate whether depression symptoms could be alleviated by an Extremely Low Frequency, Extremely Low Magnetic Environment (ELF-ELME), which has been found in basic research studies to enhance mitochondrial membrane potential. Participants were exposed to the ELF-ELME via a head-mounted magnetic field device (10 μTesla, 4 ms, 1–8 Hz/8 s) worn for 2 h per day for 8 consecutive weeks. Four male patients with treatment-resistant depression were enrolled. Significant reductions from baseline in the average total Montgomery–Åsberg Depression Rating Scale (MADRS) score were observed at 4, 6, and 8 weeks. ELF-ELME appears to ameliorate depressive symptoms in patients with major depressive disorder safely and effectively, suggesting that it could be used as an alternative treatment for depressive patients who do not prefer to take antidepressants and in combination with antidepressant therapy for patients who only partially respond to pharmacotherapy. |
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言語 |
en |
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内容記述タイプ |
Abstract |
出版者 |
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言語 |
en |
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出版者 |
Elsevier |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
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タイプ |
journal article |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
関連情報 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.ajp.2024.104036 |
収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
18762018 |
書誌情報 |
en : Asian Journal of Psychiatry
巻 96,
p. 104036,
発行日 2024-06
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ファイル公開日 |
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日付 |
2025-06-01 |
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日付タイプ |
Available |