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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 77(3)

Long-term effects of tolvaptan in patients requiring recurrent hospitalization for heart failure

https://doi.org/10.18999/nagjms.77.3.355
https://doi.org/10.18999/nagjms.77.3.355
ed77bfdf-20ec-4d5e-9b24-4c8bf9e693dd
名前 / ファイル ライセンス アクション
14_Ogawa.pdf 14_Ogawa.pdf (170.4 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-09-07
タイトル
タイトル Long-term effects of tolvaptan in patients requiring recurrent hospitalization for heart failure
著者 Ogawa, Hayato

× Ogawa, Hayato

WEKO 60360

Ogawa, Hayato

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Ajioka, Masayoshi

× Ajioka, Masayoshi

WEKO 60361

Ajioka, Masayoshi

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Ishii, Hideki

× Ishii, Hideki

WEKO 60362

Ishii, Hideki

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Okumura, Takahiro

× Okumura, Takahiro

WEKO 60363

Okumura, Takahiro

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Murase, Yosuke

× Murase, Yosuke

WEKO 60364

Murase, Yosuke

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Osanai, Hiroyuki

× Osanai, Hiroyuki

WEKO 60365

Osanai, Hiroyuki

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Nakasima, Yoshihito

× Nakasima, Yoshihito

WEKO 60366

Nakasima, Yoshihito

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Asano, Hiroshi

× Asano, Hiroshi

WEKO 60367

Asano, Hiroshi

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Sakai, Kazuyoshi

× Sakai, Kazuyoshi

WEKO 60368

Sakai, Kazuyoshi

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Murohara, Toyoaki

× Murohara, Toyoaki

WEKO 60369

Murohara, Toyoaki

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キーワード
主題Scheme Other
主題 tolvaptan
キーワード
主題Scheme Other
主題 heart failure
キーワード
主題Scheme Other
主題 hospitalization
抄録
内容記述 Although reports suggest that tolvaptan does not reduce survival or subsequent hospitalization rates in heart failure patients, its continuous use has shown good outcomes in some patients who cannot be effectively managed with high doses of loop diuretics. Therefore, we investigated the association of patient characteristics and continued tolvaptan use in heart failure patients with changes in the frequency and annual duration of patient hospitalization due to heart failure. We carefully reviewed the medical records of patients hospitalized due to heart failure who began tolvaptan therapy and continued with outpatient treatment between December 2010 and November 2013 (tolvaptan group); patients hospitalized for heart failure between May 2008 and March 2009 served as controls. We set the reference dates as the start of tolvaptan therapy (tolvaptan group) or as the date of admission (control group). The changes in hospitalization frequency and total hospitalization time due to heart failure, before and after the reference dates, were not significantly different between the tolvaptan and control groups. In the tolvaptan group, a high estimated glomerular filtration rate was a predictor of decreased hospitalization. Continuous tolvaptan use did not decrease hospitalization duration in all heart failure patients, but good renal function was predictive of a good response.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.77.3.355
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 77, 号 3, p. 355-362, 発行日 2015-08
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/773.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/22981
識別子タイプ HDL
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