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The prognostic impact of pulmonary metastasectomy in recurrent gynecologic cancers: a retrospective single-institution study
https://doi.org/10.18999/nagjms.77.3.363
https://doi.org/10.18999/nagjms.77.3.3637157bb6a-cd16-453f-a418-bf40f0b4b5ae
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
15_Adachi.pdf (272.7 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-09-07 | |||||
| タイトル | ||||||
| タイトル | The prognostic impact of pulmonary metastasectomy in recurrent gynecologic cancers: a retrospective single-institution study | |||||
| 言語 | en | |||||
| 著者 |
Adachi, Manabu
× Adachi, Manabu× Mizuno, Mika× Mitsui, Hiroko× Kajiyama, Hiroaki× Suzuki, Shiro× Sekiya, Ryuichiro× Utsumi, Fumi× Shibata, Kiyosumi× Taniguchi, Tetsuo× Kawaguchi, Koji× Yokoi, Kohei× Kikkawa, Fumitaka |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | pulmonary metastasectomy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | lung metastasis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | prognosis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | uterine cancer | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | ovarian cancer | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The aim was to examine the impact of pulmonary metastasectomy in patients with recurrent gynecologic cancers. Thirty-seven patients with isolated lung metastases (< 3 nodules) in recurrent epithelial gynecologic cancers were treated at Nagoya University Hospital between 1985 and 2013. The clinicopathological data for the 23 patients who underwent surgical resection were retrospectively analyzed, and their survival was compared with patients who received chemotherapy only. The median age at the time of surgery was 56 years (range 28–77). The studied population comprised 7 patients with 2 or 3 nodules and 8 patients with chemoresistant tumors, including fourteen cervical, 4 endometrial, and 5 ovarian primary tumors, with 5-year overall survivals (OSs) after surgery of 61, 100, and 100%, respectively. The survival of recurrence-free interval after initial treatment (>2 years) was significantly favorable (5-year OS 100% vs. 41.7%, p=0.006). Among the 6 patients with re-recurrence of lung metastases, 5 patients underwent a second pulmonary metastasectomy, and all of the patients are currently alive without disease. None of the 29 operations yielded severe complications. Although the survival rate showed a tendency to be higher in the surgery group than in the chemotherapy-only group, no significant difference was observed (5-year OS 81.7% vs. 49.5%, p=0.072). Our results indicate that pulmonary metastasectomy contributed to long-term survival with a low-risk of complications. Surgery to remove isolated lung metastases might provide a favorable prognosis for patients with long recurrence-free intervals and for patients with chemoresistant or re-recurrent tumors. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University Graduate School of Medicine, School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.77.3.363 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/773.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 77, 号 3, p. 363-372, 発行日 2015-08 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/22982 | |||||
| 識別子タイプ | HDL | |||||
