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Short treatment time and excellent treatment outcome in accelerated hyperfractionated radiotherapy for T1 glottic cancer
https://doi.org/10.18999/nagjms.77.4.585
https://doi.org/10.18999/nagjms.77.4.585b49fc692-0fc7-470e-9f43-2766fae0514d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
14_Tamaki.pdf (172.6 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-11-24 | |||||
| タイトル | ||||||
| タイトル | Short treatment time and excellent treatment outcome in accelerated hyperfractionated radiotherapy for T1 glottic cancer | |||||
| 言語 | en | |||||
| 著者 |
Tamaki, Yukihisa
× Tamaki, Yukihisa× Hieda, Yoko× Yoshida, Rika× Yoshizako, Takeshi× Fuchiwaki, Takafumi× Aoi, Noriaki× Sekihara, Kazumasa× Kitajima, Kazuhiro× Kawauchi, Hideyuki× Kitagaki, Hajime× Sasaki, Ryohei× Inomata, Taisuke |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | glottic cancer | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | accelerated hyperftactionted radiotherapy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | overall treatment time | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | local control rate | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | safety | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Accelerated hyperfractionated radiotherapy was performed as treatment for patients with T1 glottic cancer, and its utility was evaluated based on treatment outcomes and adverse effects. Fifty-eight men who had undergone radiotherapy were retrospectively reviewed. Tumor classification was Tis in 4 patients, T1a in 38, and T1b in 16. Histological examination revealed squamous cell carcinoma in 55 patients. Travel time from home to hospital was 0–1 hour for 24 patients, 1–2 hours for 9, and >2 hours for 25. Laser vaporization was performed prior to radiotherapy in 38 patients, and 19 patients received concurrent chemotherapy with an agent such as S-1. Patients were irradiated twice daily using an irradiation container. Most patients received a dose of 1.5 Gy/fraction up to a total of 60 Gy. The median overall treatment time was 30 days, with a median observation period of 59.6 months. A complete response was observed in all patients. The 5-year overall survival, disease-free survival, and local control rates were 97.2%, 93.2%, and 97.8%, respectively. Although grade 3 pharyngeal mucositis was observed in 2 patients, there were no other grade 3 or higher acute adverse events. As late toxicity, grade 2 laryngeal edema and grade 1 laryngeal hemorrhage were observed in 1 patient each, but no serious events such as laryngeal necrosis or laryngeal stenosis were observed. In conclusion, this treatment method brings excellent outcome and will substantially reduce the treatment duration among patients who need to stay at nearby hotels while undergoing treatment at hospitals in rural areas. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University Graduate School of Medicine, School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.77.4.585 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/774.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 77, 号 4, p. 585-594, 発行日 2015-11 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/23223 | |||||
| 識別子タイプ | HDL | |||||
