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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 77(4)

Short treatment time and excellent treatment outcome in accelerated hyperfractionated radiotherapy for T1 glottic cancer

https://doi.org/10.18999/nagjms.77.4.585
https://doi.org/10.18999/nagjms.77.4.585
b49fc692-0fc7-470e-9f43-2766fae0514d
名前 / ファイル ライセンス アクション
14_Tamaki.pdf 14_Tamaki.pdf (172.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-11-24
タイトル
タイトル Short treatment time and excellent treatment outcome in accelerated hyperfractionated radiotherapy for T1 glottic cancer
著者 Tamaki, Yukihisa

× Tamaki, Yukihisa

WEKO 60951

Tamaki, Yukihisa

Search repository
Hieda, Yoko

× Hieda, Yoko

WEKO 60952

Hieda, Yoko

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Yoshida, Rika

× Yoshida, Rika

WEKO 60953

Yoshida, Rika

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Yoshizako, Takeshi

× Yoshizako, Takeshi

WEKO 60954

Yoshizako, Takeshi

Search repository
Fuchiwaki, Takafumi

× Fuchiwaki, Takafumi

WEKO 60955

Fuchiwaki, Takafumi

Search repository
Aoi, Noriaki

× Aoi, Noriaki

WEKO 60956

Aoi, Noriaki

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Sekihara, Kazumasa

× Sekihara, Kazumasa

WEKO 60957

Sekihara, Kazumasa

Search repository
Kitajima, Kazuhiro

× Kitajima, Kazuhiro

WEKO 60958

Kitajima, Kazuhiro

Search repository
Kawauchi, Hideyuki

× Kawauchi, Hideyuki

WEKO 60959

Kawauchi, Hideyuki

Search repository
Kitagaki, Hajime

× Kitagaki, Hajime

WEKO 60960

Kitagaki, Hajime

Search repository
Sasaki, Ryohei

× Sasaki, Ryohei

WEKO 60961

Sasaki, Ryohei

Search repository
Inomata, Taisuke

× Inomata, Taisuke

WEKO 60962

Inomata, Taisuke

Search repository
キーワード
主題Scheme Other
主題 glottic cancer
キーワード
主題Scheme Other
主題 accelerated hyperftactionted radiotherapy
キーワード
主題Scheme Other
主題 overall treatment time
キーワード
主題Scheme Other
主題 local control rate
キーワード
主題Scheme Other
主題 safety
抄録
内容記述 Accelerated hyperfractionated radiotherapy was performed as treatment for patients with T1 glottic cancer, and its utility was evaluated based on treatment outcomes and adverse effects. Fifty-eight men who had undergone radiotherapy were retrospectively reviewed. Tumor classification was Tis in 4 patients, T1a in 38, and T1b in 16. Histological examination revealed squamous cell carcinoma in 55 patients. Travel time from home to hospital was 0–1 hour for 24 patients, 1–2 hours for 9, and >2 hours for 25. Laser vaporization was performed prior to radiotherapy in 38 patients, and 19 patients received concurrent chemotherapy with an agent such as S-1. Patients were irradiated twice daily using an irradiation container. Most patients received a dose of 1.5 Gy/fraction up to a total of 60 Gy. The median overall treatment time was 30 days, with a median observation period of 59.6 months. A complete response was observed in all patients. The 5-year overall survival, disease-free survival, and local control rates were 97.2%, 93.2%, and 97.8%, respectively. Although grade 3 pharyngeal mucositis was observed in 2 patients, there were no other grade 3 or higher acute adverse events. As late toxicity, grade 2 laryngeal edema and grade 1 laryngeal hemorrhage were observed in 1 patient each, but no serious events such as laryngeal necrosis or laryngeal stenosis were observed. In conclusion, this treatment method brings excellent outcome and will substantially reduce the treatment duration among patients who need to stay at nearby hotels while undergoing treatment at hospitals in rural areas.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.77.4.585
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 77, 号 4, p. 585-594, 発行日 2015-11
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/774.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/23223
識別子タイプ HDL
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