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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 78(1)

Nivolumab for the treatment of malignant melanoma in a patient with pre-existing myasthenia gravis

https://doi.org/10.18999/nagjms.78.1.119
https://doi.org/10.18999/nagjms.78.1.119
a998717f-b9ed-4661-9498-be572300b705
名前 / ファイル ライセンス アクション
31_Maeda.pdf 31_Maeda.pdf (322.9 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-02-23
タイトル
タイトル Nivolumab for the treatment of malignant melanoma in a patient with pre-existing myasthenia gravis
著者 Maeda, Osamu

× Maeda, Osamu

WEKO 61959

Maeda, Osamu

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Yokota, Kenji

× Yokota, Kenji

WEKO 61960

Yokota, Kenji

Search repository
Atsuta, Naoki

× Atsuta, Naoki

WEKO 61961

Atsuta, Naoki

Search repository
Katsuno, Masahisa

× Katsuno, Masahisa

WEKO 61962

Katsuno, Masahisa

Search repository
Akiyama, Masashi

× Akiyama, Masashi

WEKO 61963

Akiyama, Masashi

Search repository
Ando, Yuichi

× Ando, Yuichi

WEKO 61964

Ando, Yuichi

Search repository
キーワード
主題Scheme Other
主題 malignant melanoma
キーワード
主題Scheme Other
主題 nivolumab
キーワード
主題Scheme Other
主題 anti-programmed death 1 (PD-1) monoclonal antibody
キーワード
主題Scheme Other
主題 myasthenia gravis
キーワード
主題Scheme Other
主題 creatine phosphokinase
抄録
内容記述 A 79-year-old man with lymph node recurrence of malignant melanoma received nivolumab, an antiprogrammed death 1 (PD-1) monoclonal antibody. He had pre-existing ocular myasthenia gravis (MG) and a continued small amount of corticosteroid. Grade 3 creatine phosphokinase elevation appeared after two doses of nivolumab, and the treatment was postponed until it improved to grade 1. After three doses of nivolumab, he experienced diplopia and facial muscle weakness which were consistent with an acute exacerbation of MG, and the symptoms relieved without additional treatment for MG. He achieved shrinkage of metastasis after ten doses of nivolumab. Although a case who died due to MG after administration of nivolumab was reported recently, pre-existing MG is considered not to be always a contraindication of nivolumab.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.78.1.119
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 78, 号 1, p. 119-122, 発行日 2016-02
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/781.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/23541
識別子タイプ HDL
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