{"_buckets": {"deposit": "24f0cdff-6f2a-41bc-b431-8357de8e8ef8"}, "_deposit": {"id": "22134", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22134"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00022134"}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2016-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "193", "bibliographicPageStart": "183", "bibliographicVolumeNumber": "78", "bibliographic_titles": [{"bibliographic_title": "Nagoya Journal of Medical Science"}]}]}, "item_9_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Associations between alcohol consumption and type 2 diabetes risk are inconsistent in epidemiologic\nstudies. This study investigated the associations of ADH1B and ALDH2 polymorphisms with fasting blood\nglucose levels, and the impact of the associations of alcohol consumption with fasting blood glucose levels\nin Japanese individuals. This cross-sectional study included 907 men and 912 women, aged 35\u201369 years.\nThe subjects were selected from among the Japan Multi-institutional Collaborative Cohort study across six\nareas of Japan. The ADH1B and ALDH2 polymorphisms were genotyped by Invader Assays. The ALDH2\nGlu504Lys genotypes were associated with different levels of fasting blood glucose in men (P = 0.04).\nMean fasting glucose level was positively associated with alcohol consumption in men with the ALDH2\n504 Lys allele (Ptrend = 0.02), but not in men with the ALDH2 504Glu/Glu genotype (Ptrend = 0.45), resulting\nin no statistically significant interaction (P = 0.38). Alcohol consumption was associated with elevated\nfasting blood glucose levels compared with non-consumers in men (Ptrend = 0.002). The ADH1B Arg48His\npolymorphism was not associated with FBG levels overall or after stratification for alcohol consumption.\nThese findings suggest that the ALDH2 polymorphism is associated with different levels of fasting blood\nglucose through alcohol consumption in Japanese men. The interaction of ALDH2 polymorphisms in the\nassociation between alcohol consumption and fasting blood glucose warrants further investigation.", "subitem_description_type": "Abstract"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "URI", "subitem_identifier_uri": "http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/782.html"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/24196"}]}, "item_9_identifier_registration": {"attribute_name": "ID\u767b\u9332", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/nagjms.78.2.183", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Nagoya University Graduate School of Medicine, School of Medicine"}]}, "item_9_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "0027-7622", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yin, Guang"}], "nameIdentifiers": [{"nameIdentifier": "65648", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Naito, Mariko"}], "nameIdentifiers": [{"nameIdentifier": "65649", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Wakai, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "65650", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Morita, Emi"}], "nameIdentifiers": [{"nameIdentifier": "65651", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawai, Sayo"}], "nameIdentifiers": [{"nameIdentifier": "65652", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hamajima, Nobuyuki"}], "nameIdentifiers": [{"nameIdentifier": "65653", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Sadao"}], "nameIdentifiers": [{"nameIdentifier": "65654", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kita, Yoshikuni"}], "nameIdentifiers": [{"nameIdentifier": "65655", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takezaki, Toshiro"}], "nameIdentifiers": [{"nameIdentifier": "65656", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Keitaro"}], "nameIdentifiers": [{"nameIdentifier": "65657", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Morita, Makiko"}], "nameIdentifiers": [{"nameIdentifier": "65658", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Uemura, Hirokazu"}], "nameIdentifiers": [{"nameIdentifier": "65659", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ozaki, Etsuko"}], "nameIdentifiers": [{"nameIdentifier": "65660", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hosono, Satoyo"}], "nameIdentifiers": [{"nameIdentifier": "65661", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mikami, Haruo"}], "nameIdentifiers": [{"nameIdentifier": "65662", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kubo, Michiaki"}], "nameIdentifiers": [{"nameIdentifier": "65663", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Hideo"}], "nameIdentifiers": [{"nameIdentifier": "65664", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "16_GuangYin.pdf", "filesize": [{"value": "248.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 248500.0, "url": {"label": "16_GuangYin.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/22134/files/16_GuangYin.pdf"}, "version_id": "fbe65ae4-2dac-47ad-bad4-04ad58fc3b1f"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "ADH1B and ALDH2 polymorphisms", "subitem_subject_scheme": "Other"}, {"subitem_subject": "type 2 diabetes", "subitem_subject_scheme": "Other"}, {"subitem_subject": "fasting blood glucose", "subitem_subject_scheme": "Other"}, {"subitem_subject": "alcohol consumption", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "ALDH2 polymorphism is associated with fasting blood glucose through alcohol consumption in Japanese men", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "ALDH2 polymorphism is associated with fasting blood glucose through alcohol consumption in Japanese men"}]}, "item_type_id": "9", "owner": "1", "path": ["499/508/509/1866"], "permalink_uri": "https://doi.org/10.18999/nagjms.78.2.183", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2016-05-23"}, "publish_date": "2016-05-23", "publish_status": "0", "recid": "22134", "relation": {}, "relation_version_is_last": true, "title": ["ALDH2 polymorphism is associated with fasting blood glucose through alcohol consumption in Japanese men"], "weko_shared_id": null}